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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: Improving pandemic influenza risk assessment

    Colin A Russell et al.
    Predicting the pandemic potential of influenza viruses from genetic sequence data could transform pandemic risk assessment but progress towards this goal will require the integration of experimental work, computational tools, and virus surveillance.
    1. Developmental Biology and Stem Cells

    Reproduction: What is a placental mammal anyway?

    Patrick Abbot, John A Capra
    Many developmental functions in marsupials and eutherian mammals are accomplished by different tissues, but similar genes.
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    1. Cell Biology

    Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish

    Tokiro Ishikawa et al.
    The unfolded protein response sensor/transducer IRE1-mediated splicing of XBP1 mRNA encoding its active downstream transcription factor to maintain the homeostasis of the endoplasmic reticulum is sufficient for growth and development of medaka fish.
    1. Developmental Biology and Stem Cells

    Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1

    Antonio Galeone et al.
    N-glycanase 1 is required for a BMP autoregulatory loop in the visceral mesoderm and for intestinal development in Drosophila.
    1. Neuroscience

    Selective rab11 transport and the intrinsic regenerative ability of CNS axons

    Hiroaki Koseki et al.
    Mature axons lose the ability to regenerate because key growth molecules are excluded through changes in vesicle transport, and restoring transport can restore regeneration.
    1. Neuroscience

    Motoneurons regulate the central pattern generator during drug-induced locomotor-like activity in the neonatal mouse

    Melanie Falgairolle et al.
    Motoneuron activity provides feedback to the spinal network responsible for generating locomotion in the developing mouse spinal cord.
    1. Cell Biology

    Ubiquitylation-independent activation of Notch signalling by Delta

    Nicole Berndt et al.
    Analysis of a variant without lysine in the intracellular domain reveals a ubiquitylation-independent signalling activity of the DSL ligand Delta and novel functions of the Neuralized and Mindbomb1 E3-ligases during Notch signalling.
    1. Neuroscience

    Gyrification of the cerebral cortex requires FGF signaling in the mammalian brain

    Naoyuki Matsumoto et al.
    FGF signaling is crucial for gyrus formation, proliferation of outer radial glial cells and expansion of upper layers of the cerebral cortex in gyrencephalic mammals.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Nuclear microenvironments modulate transcription from low-affinity enhancers

    Albert Tsai et al.
    Efficient transcription from low-affinity enhancers is driven by nuclear microenvironments of transcription factors.