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    1. Computational and Systems Biology
    2. Neuroscience

    A kinematic synergy for terrestrial locomotion shared by mammals and birds

    Giovanna Catavitello et al.
    General principles of the limb segment control for terrestrial locomotion have emerged in evolution and highlight the existence of the laws of biological motion that apply to various animal species.
    1. Ecology
    2. Microbiology and Infectious Disease

    Immune-mediated hookworm clearance and survival of a marine mammal decrease with warmer ocean temperatures

    Mauricio Seguel et al.
    In years with colder ocean temperatures, fur seal pups receive more maternal care and have a better energy balance, clearing hookworm infection earlier, which increases their chances of survival.
    1. Neuroscience

    Balance between BDNF and Semaphorins gates the innervation of the mammary gland

    Hadas Sar Shalom et al.
    The innervation of the mammary gland is controlled by opposing effects of neurotrophic and repulsive factors and, once trophic signaling is inhibited the repulsive factors, may promote axonal pruning.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Recurrent loss of HMGCS2 shows that ketogenesis is not essential for the evolution of large mammalian brains

    David Jebb, Michael Hiller
    The evolutionary loss of the main enzyme required for ketone body biosynthesis suggests that alternative strategies to provide energy for large brains during fasting evolved repeatedly in mammals.
    1. Evolutionary Biology

    Subterranean mammals show convergent regression in ocular genes and enhancers, along with adaptation to tunneling

    Raghavendran Partha et al.
    Repeated evolution of eye regression in subterranean mammals helps identify genes and regulatory elements involved in visual perception and development of the eye, and predicts candidate sequences with a potential role in ocular disorders.
    1. Ecology
    2. Genetics and Genomics

    Education and Outreach: March Mammal Madness and the power of narrative in science outreach

    Katie Hinde et al.
    Hypothetical battles between animals can be used to interest the general public in biology.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Immune genes are hotspots of shared positive selection across birds and mammals

    Allison J Shultz, Timothy B Sackton
    Pathogens, particularly viruses, target the same genes over deep evolutionary time, resulting in shared signatures of positive selection and transcriptional responses at the same genes.
    1. Cell Biology
    2. Cancer Biology

    Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters

    Alexandra Naba et al.
    Many extracellular matrix proteins that are up-regulated during breast tumor progression enhance metastasis, and some are prognostic indicators of poor survival.
    1. Developmental Biology

    Molecular conservation of marsupial and eutherian placentation and lactation

    Michael W Guernsey et al.
    The short-lived tammar wallaby placenta expresses genes resembling eutherian placentas, establishing marsupials as "placental mammals", further, dynamic lactation allows marsupials to compensate for short placentation by expressing key placental genes in the mammary gland.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Hemozoin produced by mammals confers heme tolerance

    Rini H Pek et al.
    Heme accumulation is toxic, but deficiency of the heme transporter HRG1/SLC48A1 causes heme sequestration and crystallization into hemozoin within enlarged lysosomes of macrophages, thereby conferring heme tolerance to mammals.