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    1. Cell Biology

    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

    Fan Zhang, Yuan Wang ... Xianpeng Ge
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Trans regulation of an odorant binding protein by a proto-Y chromosome affects male courtship in house fly

    Pablo J Delclos, Kiran Adhikari ... Richard Meisel
    An integrative approach is used to identify a mechanism by which the fitness effects of Y chromosomes can manifest via trans effects on autosomal genes, through their effects on male courtship and other sexually selected traits.
    1. Evolutionary Biology

    Evolution of novel mimicry polymorphisms through Haldane’s sieve and rare recombination

    Riddhi Deshmukh, Saurav Baral ... Krushnamegh Kunte
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Inhibitors of the small membrane (M) protein viroporin prevent Zika virus infection

    Emma Brown, Gemma Swinscoe ... Stephen Griffin
    A new way to treat Zika virus infections could be achieved following the definition of an ion channel function for the M protein within virus particles.
    1. Genetics and Genomics

    An in vitro approach reveals molecular mechanisms underlying endocrine disruptor-induced epimutagenesis

    Jake D Lehle, Yu-Huey Lin ... John R McCarrey
    The utility of an in vitro cell culture system for studies of molecular mechanisms underlying the initial induction and subsequent propagation of environmentally induced epimutations is demonstrated.
    1. Neuroscience

    The function of juvenile–adult transition axis in female sexual receptivity of Drosophila melanogaster

    Jing Li, Chao Ning ... Chuan Zhou
    Prothoracicotropic hormone and ecdysone belonging to the insect PG axis modulate virgin female sexual receptivity.
    1. Genetics and Genomics

    Dynamics of transcriptional programs and chromatin accessibility in mouse spermatogonial cells from early postnatal to adult life

    Irina Lazar-Contes, Rodrigo G Arzate-Mejia ... Isabelle M Mansuy
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Immunology and Inflammation

    Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity

    Zhixin Jing, Phillip Galbo ... David Fooksman
    Enigmatic long-lived plasma cells display an enhanced clustering in bone marrow niches and require CXCR4 for retention, survival, and maintenance of antibody titers.
    1. Neuroscience

    LRRK2 regulates synaptic function through BDNF signaling and actin cytoskeleton

    Giulia Tombesi, Shiva Kompella ... Elisa Greggio
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid