The mouse gene Ythdc2 exemplifies an evolutionarily ancient family of crucial regulators of the transition from germline stem cell divisions to meiosis.
Byron C Williams, Joshua J Filter ... Michael L Goldberg
The mechanism of inhibition by unfair competition is central to determining the protein phosphorylation states that govern cell cycle transitions between M phase and interphase.
Radhika A Varier, Theodora Sideri ... Folkert J van Werven
N6-methyladenosine (m6A) reader Pho92 is directed by Paf1C to meiotic mRNAs in an m6A-dependent and independent manner and promotes CCR4-NOT-mediated mRNA decay of m6A modified transcripts contingent on translation.
Single-cell transcriptomics of the zebrafish ovary identifies both major and minor cell types and provides a valuable resource for researchers interested in reproductive biology, stem cell biology, and aquatic toxicology.
Kishore R Mosaliganti, Ian A Swinburne ... Sean G Megason
Size regulation of the otic vesicle, the progenitor of the inner ear, is mediated by mechanical feedback involving fluid influx, hydraulic pressure, and tissue mechanics.
Alex Hunt, Matthew Robert Geoffrey Russell ... Moritz Treeck
Partially overlapping functions of a limited subset of actin binding proteins allow the parasite Toxoplasma gondii to achieve actin regulation required for complex cellular processes.