Acetylcholine, released from cholinergic fibers originating from the medial septum, shapes social memory, and controls the CA2 hippocampal circuit via nicotinic receptors localized on GABAergic interneurons.
Combining cerebral organoid technology with cryo-correlative microscopy reveals the organization of cytoskeleton, membrane compartments, and protein synthesis machinery contributing to the rapid expansion of developing human axons.
Digital reconstruction of environment combined with eye and head-tracking enabled the process of prey-detection and capture to be seen from the freely moving mouse’s point-of-view and shows the exact visual-field and retinal location mice use when chasing prey and the advantage.
CA1 and PFC bridge the temporal gap between cue and reward delivery during trace conditioning according to different underlying coding principles and task-related activity is reactivated during awake Sharp-Wave Ripples.
Alternative splicing and the endoplasmic reticulum (ER)-associated protein degradation (ERAD) system represent essential, fat depot-specific components of the adipogenesis that are altered in preadipocytes from obese individuals with metabolic disease.
Assessments using chemogenetic and pharmacological approaches reveal that modulation of the activities of oxytocin neurons in the hypothalamus of the central nervous system could inhibit colorectal cancer progression in mice.