131 results found
    1. Neuroscience

    Decoding odor quality and intensity in the Drosophila brain

    Antonia Strutz, Jan Soelter ... Silke Sachse
    The lateral horn can be classified into three functional odor response domains that decode opposing hedonic valences and odor intensity.
    1. Neuroscience

    The number of olfactory stimuli that humans can discriminate is still unknown

    Richard C Gerkin, Jason B Castro
    The recent claim that humans can discriminate more than one trillion odors is shown to be unwarranted.
    1. Neuroscience

    Multivariate analysis of electrophysiological diversity of Xenopus visual neurons during development and plasticity

    Christopher M Ciarleglio, Arseny S Khakhalin ... Carlos D Aizenman
    The diversity of electrophysiological phenotypes of neurons in a functional network increases over development, but can be modulated, and even reduced by sensory experience; allowing them to adapt to a changing and growing brain.
    1. Neuroscience

    Dendritic nonlinearities are tuned for efficient spike-based computations in cortical circuits

    Balázs B Ujfalussy, Judit K Makara ... Máté Lengyel
    Dendrites combine the inputs that they receive from other neurons using calculations that have been optimized for those particular input patterns.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    An integrative transcriptomic atlas of organogenesis in human embryos

    Dave T Gerrard, Andrew A Berry ... Neil A Hanley
    Integrating human embryonic transcriptomes from 15 sites during organogenesis identifies novel expression signatures linked to congenital disorders and a new programme of non-coding gene expression.
    1. Neuroscience

    Behavioral-state modulation of inhibition is context-dependent and cell type specific in mouse visual cortex

    Janelle MP Pakan, Scott C Lowe ... Nathalie L Rochefort
    The three main types of inhibitory neurons in mouse primary visual cortex respond differently to locomotion in darkness and during visual stimulation, revealing context-dependent responses to changes in behavioral state.
    1. Computational and Systems Biology
    2. Neuroscience

    Cell assemblies at multiple time scales with arbitrary lag constellations

    Eleonora Russo, Daniel Durstewitz
    A novel statistical algorithm for mining high-dimensional spike train (count) data for significant spatio-temporal patterns reveals new insights into task and brain area dependent functional organization of neural activity.
    1. Neuroscience

    Optimal compensation for neuron loss

    David GT Barrett, Sophie Denève, Christian K Machens
    Spiking networks compensate the loss of neurons instantaneously, when restoration of excitatory/inhibitory balance becomes equivalent to restoration of functionality.
    1. Computational and Systems Biology
    2. Neuroscience

    Microsaccadic sampling of moving image information provides Drosophila hyperacute vision

    Mikko Juusola, An Dau ... Jouni Takalo
    New experiments and theory reveal how the ability to see image details depends upon photoreceptor function and eye movements, and how fruit flies (Drosophila) see spatial details beyond the optical limit of their compound eyes.
    1. Neuroscience

    Two-photon calcium imaging of the medial prefrontal cortex and hippocampus without cortical invasion

    Masashi Kondo, Kenta Kobayashi ... Masanori Matsuzaki
    Establishment of two-photon imaging with a 1100-nm laser, which underfills the objective's back aperture, detects activity of multiple neurons in the prelimbic area and hippocampal CA1 region of the intact mouse brain.

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