1,081 results found
    1. Neuroscience

    Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation

    James B Isbister, András Ecker ... Michael W Reimann
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Conformational changes, excess area, and elasticity of the Piezo protein-membrane nanodome from coarse-grained and atomistic simulations

    Sneha Dixit, Frank Noé, Thomas R Weikl
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Neuroscience

    Pain persists in mice lacking both Substance P and CGRPα signaling

    Donald Iain MacDonald, Monessha Jayabalan ... Alexander Chesler
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Developmental Biology
    2. Cancer Biology

    Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

    Denise Ragusa, Chun-Wai Suen ... Cristina Pina
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Structural Biology and Molecular Biophysics

    Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments

    Jessica Flowers, Nathaniel Echols ... Stephanie A Wankowicz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

    Sujeethkumar Prithiviraj, Alejandro Garcia Garcia ... Paul E Bourgine
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Disentangling acute motor deficits and adaptive responses evoked by the loss of cerebellar output

    Nirvik Sinha, Sharon Israely ... Yifat Prut
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution

    Julie Uveira, Antoine Donati ... Tsuyoshi Momose
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Cancer Biology

    Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis

    Zuzana Outla, Gizem Oyman-Eyrilmez ... Martin Gregor
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Inversions Can Accumulate Balanced Sexual Antagonism: Evidence from Simulations and Drosophila Experiments

    Christopher S McAllester, John E Pool
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
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