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The generalizability of CODOP in distinct world regions and its flexibility to reckon with the changing availability of hospital resources makes it a clinically useful tool potentially improving the outcome prediction and the management of COVID-19 hospitalized patients.

Cells called alveolar myofibroblasts, which have a central role in the development of the lung after birth, receive an orchestrated input from a range of different signaling pathways.

When mice run, their breathing frequency increases but breaths are not temporally synchronized to strides at any speed or gait.

Sepsis-induced long-term muscle weakness was reproduced using a refined murine model, which was accompanied by mitochondrial dysfunction in the absence of sustained atrophy, suggesting the promise of mitochondria-targeted post-sepsis therapies.

A vasoactive molecular imaging probe provides capability for sensitive functional imaging of cancer-associated protease activity in vivo.

Nebulized dornase alfa endonuclease reduces inflammation, coagulopathy, and the length of hospitalization in individuals with severe COVID-19 pneumonia.

Using simultaneous recordings of electrophysiology, respiration, and resting-state fMRI, a respiration-associated neural network is identified.

Compared with casirivimab/imdevimab and bamlanivimab/etesevimab, early treatment with sotrovimab seems to reduce the time to sustained recovery among adult outpatients with mild-to-moderate SARS-CoV-2 infection due to Omicron BA.1 and BA.1.1.

Networked cardiac control, revealed through analysis of extended baseline-state multi-channel recordings, differentiates heart failure and normal regimes highlighting the promise of peripheral neurally based clinical interventions.

A novel species-specific detection method could obtain pathogenic bacteria information in 4 hr with high clinical sensitivity and specificity, which guided the faster antibiotic treatment in ICU and brought some clinical benefit in a real-world scenario.