232 results found
    1. Computational and Systems Biology
    2. Physics of Living Systems

    How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective

    Joseph Ackermann, Chiara Bernard ... Martine Ben Amar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Physics of Living Systems

    Probing the force-from-lipid mechanism with synthetic polymers

    Miranda L Jacobs, Jan Steinkühler ... Neha P Kamat
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology
    2. Physics of Living Systems

    Self-organized patterning of cell morphology via mechanosensitive feedback

    Natalie A Dye, Marko Popović ... Frank Jülicher
    Radial patterns of cell morphology in the Drosophila larval wing emerge through mechanosensitive dynamics of cell polarity.
    1. Developmental Biology
    2. Neuroscience

    Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis

    Rachel C. Clary, Blair A. Jenkins, Ellen A. Lumpkin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology

    Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1

    Namsuk Kim, Yan Li ... Won-Jong Oh
    Repulsive guidance cues enhance a dual-functioning axonal trafficking facilitator, allowing navigating axons to ensure proper pathfinding by coordinating positive extension and negative steering during nervous system development.
    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

    Kentarou Baba, Wataru Yoshida ... Naoyuki Inagaki
    Shootin1a, through its spatially regulated phosphorylation within growth cones, mediates the gradient reading and mechanoresponse for netrin-1-induced axon guidance.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex

    Nicole Merritt, Keith Garcia ... Munir R Tanas
    The C terminal fusion partners of TAZ-CAMTA1, YAP-TFE3 and potentially other TAZ/YAP fusion proteins in cancer recruit epigenetic modifiers that modulate a baseline TEAD-based transcriptional program.
    1. Cell Biology
    2. Physics of Living Systems

    A mechano-osmotic feedback couples cell volume to the rate of cell deformation

    Larisa Venkova, Amit Singh Vishen ... Matthieu Piel
    Whether deforming cells behave as elastic balls (deforming at constant volume) or as sponges (loosing volume as they deform) depends on how fast they change their shape, because the cell volume depends on the tension of the plasma membrane.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells

    Daniela Ávila-González, Wendy Portillo ... Néstor F Díaz
    Interaction of human embryonic stem cells (hESC) with human amniotic epithelial cells (hAEC) confers hESC a pluripotent potential that resembles the anteriorized epiblast, which is predisposed to form the neural ectoderm.

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