Historical analysis of nearly half-a-million articles from the Journal of the American Medical Association and the New England Journal of Medicine since their inception frames the shifting scientific, material, ethical, and epistemic underpinnings of medicine over time, including today.

An analysis of more than 3000 randomized controlled trials published in JAMA, the Lancet and NEJM has identified 396 medical reversals.

Lockdowns in the United States caused by the COVID-19 pandemic appear related to a decrease in the number of women publishing research papers, especially as first authors.

Comprehensive decade-long analysis of point-of-care resources reveals insights into how clinical research makes its way into practice across different medical specialties and through time to enable us to identify potential translational bottlenecks in the pathway from research to practice.

In studies of gender disparities in academia, increased focus is required on within-group variability and between-group overlap of distributions when interpreting and reporting results.

Journals and other scientific organizations produce a diverse variety of plain-language summaries.

The availability of almost all articles from toll access journals in the Sci-Hub repository will disrupt scholarly publishing towards more open models.

Sex-inclusive research practices have increased in many biological disciplines over the past decade, yet critical sex-based analyses and reporting have remained stagnant in most of these disciplines.

Early career researchers commonly peer review manuscripts on behalf of invited reviewers, often without receiving feedback or being named to the journal.