13 results found
    1. Cell Biology
    2. Medicine

    MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice

    Shilpak Bele, Shravan Babu Girada ... Prasenjit Mitra
    Class 1 histone deacetylase (HDAC) inhibitor MS-275 enhances the efficacy of glucagon-like peptide 1 receptor (GLP-1R) therapy for glycemic control and reduction of obesity.
    1. Neuroscience

    The contribution of temporal coding to odor coding and odor perception in humans

    Ofer Perl, Nahum Nahum ... Rafi Haddad
    Human participants fail to discriminate between odor sequences that activate the same neurons at different orders, pointing against a substantial role for neuron activation time in the odor code.
    1. Neuroscience

    A genetic basis for molecular asymmetry at vertebrate electrical synapses

    Adam C Miller, Alex C Whitebirch ... Cecilia B Moens
    Electrical synapses are neuronal, gap-junction-based connections found throughout the nervous system that, in the escape circuit of zebrafish, are composed of molecularly distinct pre- and postsynaptic junction forming proteins that are required for behavioral performance.
    1. Neuroscience

    The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

    Peter Soba, Chun Han ... Yuh Nung Jan
    A cell surface receptor called Ret enables neurons to establish and maintain the organized arrays of dendrites that support communication between neurons.
    1. Neuroscience

    Internal states drive nutrient homeostasis by modulating exploration-exploitation trade-off

    Verónica María Corrales-Carvajal, Aldo A Faisal, Carlos Ribeiro
    A quantitative video tracking analysis reveals that to gain the nutrients they need, flies change their decisions to exploit foods with different nutrient contents and explore the environment according to their internal amino acid and reproductive states.
    1. Neuroscience

    Simultaneous activation of parallel sensory pathways promotes a grooming sequence in Drosophila

    Stefanie Hampel, Claire E McKellar ... Andrew M Seeds
    A grooming sequence is produced by a neural architecture that readies different movements simultaneously, and a mechanism where prioritized suppression between the movements determines their sequential performance.
    1. Neuroscience

    Sexually dimorphic control of gene expression in sensory neurons regulates decision-making behavior in C. elegans

    Zoë A Hilbert, Dennis H Kim
    A sexually dimorphic transcriptional switch in sensory neurons integrates information about microbial environment and nutritional state to regulate exploratory behavior in C. elegans..
    1. Immunology and Inflammation
    2. Neuroscience

    Sensing the world and its dangers: An evolutionary perspective in neuroimmunology

    Aurora Kraus, Katherine M Buckley, Irene Salinas
    The investigation of neuroimmunology in non-model organisms is critical to diversify the field and identify primordial principles that govern neuroimmune communication across taxa.
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells

    Atikul Islam, Yu-Chun Chang ... Pin Ju Chueh
    Multifaceted properties of the water-soluble derivative of antibiotic heliomycin enable it to offer greater antitumor value than its parent compound by inhibiting the tNOX-NAD+-SIRT1 axis to induce apoptosis.
    1. Computational and Systems Biology
    2. Neuroscience

    Na+/K+ pump interacts with the h-current to control bursting activity in central pattern generator neurons of leeches

    Daniel Kueh, William H Barnett ... Ronald L Calabrese
    The dynamic current generated Na+/K+ pump interacts with the h-current to control the bursting activity of oscillator heart interneurons.

Refine your results by:

Type
Research categories