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Genetics and Genomics
Cancer Biology
Combinatorial CRISPR screen reveals
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KDM4
as targets for synergistic drug combination for treating triple negative breast cancer
Tackhoon Kim, Byung-Sun Park ... Timothy K Lu
Cancer Biology
Deuterium Metabolic Imaging Phenotypes Mouse Glioblastoma Heterogeneity Through Glucose Turnover Kinetics
Rui V Simões, Rafael N Henriques ... Noam Shemesh
Cell Biology
Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility
Takahiro Yamanaka, Zimo Xiao ... Masayuki Shimada
Cell Biology
Novel Mechanism for Tubular Injury in Nephropathic Cystinosis
Swastika Sur, Maggie Kerwin ... Minnie M Sarwal
Cell Biology
Developmental Biology
Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition
Yuhkoh Satouh, Takaki Tatebe ... Ken Sato
Cell Biology
ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia
Shimin Wang, Hongxian Wang ... Dong Zhao
Structural Biology and Molecular Biophysics
Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling
Nevin K Zacharia, Stefanie Kuhns ... Esben Lorentzen
Stem Cells and Regenerative Medicine
Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial
Shiyu Zhang, Min Zhou ... Wei Zuo
Neuroscience
Stem Cells and Regenerative Medicine
Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons
Ana C Costa, Blanca R Murillo ... Monica M Sousa
Immunology and Inflammation
Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism
Wesley H Godfrey, Kaho Cho ... Michael D Kornberg
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