6,971 results found
    1. Cell Biology
    2. Neuroscience

    High N-glycan multiplicity is critical for neuronal adhesion and sensitizes the developing cerebellum to N-glycosylation defect

    Daniel Medina-Cano, Ekin Ucuncu ... Vincent Cantagrel
    Impairment of protein N-glycosylation disrupts neural cell adhesion mediated by highly glycosylated members of the IgSF-CAM protein family.
    1. Immunology and Inflammation

    Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter mice

    Laura Medina-Ruiz, Robin Bartolini ... Gerard J Graham
    The use of multi-chemokine receptor reporter mice helps to unravel the dynamics of receptor involvement in leukocyte migration in vivo and suggests specificity, rather than redundancy, in receptor use.
    1. Cell Biology

    Different translation dynamics of β- and γ-actin regulates cell migration

    Pavan Vedula, Satoshi Kurosaka ... Anna Kashina
    β- and γ-cytoplasmic actins have different translation rates in cells and exert different nucleotide coding sequence-dependent effects on cell migration.
    1. Neuroscience

    Changing the incentive structure of social media platforms to halt the spread of misinformation

    Laura K Globig, Nora Holtz, Tali Sharot
    Offering users reaction buttons that convey reliability (e.g., ‘trust’, ‘distrust’) increases discernment and significantly reduces the spread of misinformation on a social media platform.
    1. Neuroscience

    Dynamic modulation of activity in cerebellar nuclei neurons during pavlovian eyeblink conditioning in mice

    Michiel M ten Brinke, Shane A Heiney ... Chris I De Zeeuw
    Conditioned olivocerebellar network activity elicits transient spike pauses and timed spike facilitation in the neurons of interposed nuclei that predicts and likely causes conditioned eyelid responses on a trial-by-trial basis.
    1. Epidemiology and Global Health

    A review of HPV and HBV vaccine hesitancy, intention, and uptake in the era of social media and COVID-19

    Emily K Vraga, Sonya S Brady ... Shalini Kulasingam
    A review of the current empirical literature underscores the need for longitudinal research examining potential spillover effects between hesitancy, intention, or uptake for the COVID vaccine and HPV and HBV vaccines, especially to account for social media misinformation.
    1. Developmental Biology

    Drosophila medulla neuroblast termination via apoptosis, differentiation, and gliogenic switch is scheduled by the depletion of the neuroepithelial stem cell pool

    Phuong-Khanh Nguyen, Louise Y Cheng
    The termination of medulla neuroblasts is specified by the depletion of the neuroepithelium and mediated by apoptosis, differentiation, and gliogenic switch.
    1. Developmental Biology

    Endogenous protein tagging in medaka using a simplified CRISPR/Cas9 knock-in approach

    Ali Seleit, Alexander Aulehla, Alexandre Paix
    Highly efficient, precise, and scalable CRISPR/Cas9-mediated generation of endogenously tagged alleles in a vertebrate model.
    1. Developmental Biology

    Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration

    Shih-Lei Lai, Rubén Marín-Juez ... Didier YR Stainier
    Timely macrophage recruitment is essential for neovascularization and neutrophil clearance during cardiac regeneration.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Punctuated evolution and transitional hybrid network in an ancestral cell cycle of fungi

    Edgar M Medina, Jonathan J Turner ... Nicolas E Buchler
    Cell cycle network evolution in a fungal ancestor was punctuated by the arrival of a viral DNA-binding protein that was permanently incorporated into the regulatory network controlling cell cycle entry.

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