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Major cell types across various brain regions distinctively associate with tissue loss in 13 neurodegenerative conditions.

Natural Tr1-like cells do not form a functionally stable memory response to allergens, and this instability may limit efforts to re-establish tolerance by expanding Tr1.

Longitudinal transcriptomic analysis of unvaccinated patients reveals that early NK cell cytotoxicity activation distinguishes mild from severe COVID-19, supporting the relevance of concerted innate–adaptive immune responses against the virus.

Sensory-driven calcium spikes in Purkinje cells are not binary; instead, they are graded and can provide information about the strength of a periocular airpuff stimulus known to drive learning.

Piezo1 activity within keratinocytes slows healing of wounded skin via dynamic channel enrichment at regions of the wound edge, causing localized retraction and thus hindering keratinocyte migration during wound healing.

Medaka fish were able to use faces for individual recognition, and were slower to recognise inverted faces but not inverted non-face shapes.

The well-established link between stress and depression could be due to the activity of a population of cells in prefrontal cortex that express a gene mutated in the rare disorder Wolfram syndrome.

Epsin has a key role in the coupling of actin to endocytic clathrin coated pits that is required for their maturation and helps capture SNAREs at endocytic clathrin coated pits.

The uncertainties of the pandemic and the restrictions on social life have a strong impact on mental well-being, and especially on the expression of schizotypal traits, which are further boosted by excessive media consumption.

Mutations along the signaling pathway of the E. coli sensor histidine kinase PhoQ alter signal gain and ligand-sensitivity by altering thermodynamic allosteric coupling between domains.