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    1. Cell Biology
    2. Developmental Biology

    Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development

    Kasmir Ramo et al.
    The kinase JNK is required in endothelial cells for the development of native collateral arteries.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Molecular mechanism of voltage-dependent potentiation of KCNH potassium channels

    Gucan Dai, William N Zagotta
    A powerful new fluorescence approach elucidates the structural mechanism for a specialized ion channel behavior important for cardiac and neuronal excitability.
    1. Biochemistry and Chemical Biology

    An explanation for origin unwinding in eukaryotes

    Lance D Langston, Michael E O'Donnell
    CMG helicase translocates with force while encircling duplex DNA, enabling two opposing CMG complexes at an origin to melt the duplex and switch to encircling separate single strands.
    1. Cell Biology

    α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism

    Amin Khalifeh-Soltani et al.
    The milk protein Mfge8 promotes fat uptake and slows gastrointestinal motility to optimize nutrient absorption.
    1. Structural Biology and Molecular Biophysics

    Transcription: Overcoming chromatin barriers

    Babette E de Jong, John van Noort
    Single-molecule experiments reveal the dynamics of transcription through a nucleosome with single-base-pair accuracy.
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    1. Neuroscience

    Maternal Behavior: Why mother rats protect their children

    Ksenia Z Meyza, Ewelina Knapska
    The presence of the hormone oxytocin in the central amygdala makes a mother rat willing to put her life in danger in order to protect her offspring.
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    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Mitosis: Checkpoint proteins come under scrutiny

    Maria Mora-Santos, Jonathan BA Millar
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    1. Cell Biology
    2. Human Biology and Medicine

    Carcinogenesis: Targeting the link between late pregnancy and breast cancer

    Balabhadrapatruni VSK Chakravarthi, Sooryanarayana Varambally
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    1. Developmental Biology
    2. Immunology and Inflammation

    Symbiosis: Protection from within

    Florent Masson, Bruno Lemaitre
    The development of the tsetse fly immune system relies on a cue from an endosymbiotic bacterium called Wigglesworthia.
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