776 results found
    1. Cell Biology
    2. Physics of Living Systems

    Mechanically stimulated ATP release from murine bone cells is regulated by a balance of injury and repair

    Nicholas Mikolajewicz et al.
    Bone cells exposed to physiological forces release ATP through repairable membrane injury, generating an intercellular signal that conveys the destructive potential of forces and the adaptive capacity of endangered cells.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    Synergy between serum amyloid A and secretory phospholipase A2

    Shobini Jayaraman et al.
    SAA removes toxic products of lipolysis of the cell membrane by sPLA2, indicating that SAA and sPLA2 act synergistically to clear debris from injured sites, as required for tissue healing.
    1. Cell Biology

    Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons

    Pratibha Narayanan et al.
    Local Mtmr2 activity and PI(3,5)P2 abundance dynamically control Piezo2-dependent mechanotransduction in peripheral sensory neurons.
    1. Cell Biology
    2. Immunology and Inflammation

    Microtubule plus-end dynamics link wound repair to the innate immune response

    Clara Taffoni et al.
    Microtubules orchestrate wound repair and innate immune response in the Caenorhabditis elegans epidermis.
    1. Neuroscience

    Criticality and degeneracy in injury-induced changes in primary afferent excitability and the implications for neuropathic pain

    Stéphanie Ratté et al.
    No single molecular change is uniquely necessary to cause neuropathic changes in primary afferent excitability; multiple different changes are sufficient.
    1. Neuroscience

    Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD+ in axon regeneration

    Kyung Won Kim et al.
    A function-based genetic screen using the Caenorhabditis elegans axotomy model identifies new regulators and an inhibitory role for NAD+ in axon regeneration, expanding the understanding of axon injury responses and regeneration.
    1. Cell Biology
    2. Developmental Biology

    Osmolarity-independent electrical cues guide rapid response to injury in zebrafish epidermis

    Andrew S Kennard, Julie A Theriot
    Skin cells in zebrafish use sodium chloride-dependent electrical gradients to sense tissue injury and guide migration in the appropriate direction to close the wound.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Distinct origins and molecular mechanisms contribute to lymphatic formation during cardiac growth and regeneration

    Dana Gancz et al.
    Cardiac lymphatic vessels of heterogeneous origins and molecular signatures support cardiac growth and regeneration.
    1. Neuroscience

    mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system

    Linqing Miao et al.
    The kinase AKT acts as a nodal point that coordinates both positive and negative cues to regulate the regeneration of central nervous system axons in adult mice.
    1. Neuroscience

    Hidden synaptic differences in a neural circuit underlie differential behavioral susceptibility to a neural injury

    Akira Sakurai et al.
    Animal-to-animal variability in neural circuit elements is often hidden under normal conditions, but becomes functionally relevant when the system is challenged by injury.

Refine your results by:

Type
Research categories