Ivan Castello-Serrano, Frederick A Heberle ... Ilya Levental
Direct measurements of trafficking kinetics between organelles of the secretory pathway suggest that lipid-driven membrane domains laterally sort proteins during membrane traffic.
Gabriella Angiulli, Harveer Singh Dhupar ... Thomas Walz
Cryo-EM structures reveal how the peptidisc scaffold can adapt to different membrane proteins, establishing it as a universal membrane mimetic to stabilize membrane proteins in solution.
Arc-shaped PFO oligomers consisting of at least four subunits can insert into the membrane in a kinetically controlled process opening a transmembrane pore, whereby post-insertion growth may ultimately lead to formation of a complete ring.
Qian Liu, Elizabeth J Osterlund ... David William Andrews
The pro-apoptotic BH3-protein Bim contains two distinct binding sites for anti-apoptotic proteins that together confer resistance of Bim/Bcl-2 and Bim/Bcl-XL complexes to BH3-mimetic drugs under development for use in humans.
Charline Sophie Pinna, Maëlle Vilbert ... Marianne Elias
Wing transparency in mimetic butterflies and moths is achieved by an unexpected diversity of structural features, and both structures and light transmission properties of wings are under selection for convergence.