250 results found
    1. Neuroscience

    Noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation

    Josué Haubrich et al.
    The overactivation of noradrenergic inputs to the amygdala during severe fear learning increases memory stability at the expense of lability, rendering the trace resistant to memory destabilization and reconsolidation.
    1. Neuroscience

    Odor-evoked category reactivation in human ventromedial prefrontal cortex during sleep promotes memory consolidation

    Laura K Shanahan et al.
    Odor cues in sleep evoke content-specific signatures of neural reactivation in visual and prefrontal brain areas that predict subsequent memory performance in the wake state.
    1. Neuroscience

    Enhancement of fear memory by retrieval through reconsolidation

    Hotaka Fukushima et al.
    Retrieval enhances fear memory through reconsolidation by activating calcineurin-induced protein degradation and CREB-mediated gene expression in amygdala, hippocampus, and mPFC.
    1. Neuroscience

    Role of protein synthesis and DNA methylation in the consolidation and maintenance of long-term memory in Aplysia

    Kaycey Pearce et al.
    Behavioral and synaptic investigations of long-term memory in Aplysia reveal differing roles for DNA methylation, protein synthesis during training and protein synthesis shortly after training with respect to memory consolidation and maintenance.
    1. Neuroscience

    New learning while consolidating memory during sleep is actively blocked by a protein synthesis dependent process

    Roi Levy et al.
    The brain inhibits the formation of new memories just after waking to safeguard the ongoing stabilization of existing memories during sleep.
    1. Neuroscience

    Parvalbumin-positive interneurons mediate neocortical-hippocampal interactions that are necessary for memory consolidation

    Frances Xia et al.
    Electrophysiological and behavioural experiments reveal that parvalbumin interneuron-mediated increases in neocortical-hippocampal interactions are necessary for successful memory consolidation.
    1. Neuroscience

    5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex

    Juan Facundo Morici et al.
    Serotonin, a neurotransmitter mostly studied in relation with emotions, also plays an important role in the control of episodic memories.
    1. Neuroscience

    Activation of astrocytes in hippocampus decreases fear memory through adenosine A1 receptors

    Yulan Li et al.
    A new strategy of memory consolidation disruption based on astrocyte and purinergic signaling, which leads to persistent fear memory attenuation accompanied by reduced fear-related anxiety behavior.
    1. Neuroscience

    A role for CIM6P/IGF2 receptor in memory consolidation and enhancement

    Xiao-Wen Yu et al.
    Cation-independent-mannose-6-phosphate-receptor, or insulin-like-growth-factor-2-receptor (CIM6P/IGF2R) expressed in the hippocampus controls the protein metabolism regulated by learning and required for memory consolidation, and is also a key mechanism for memory enhancement.
    1. Neuroscience

    A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster

    Paula R Haynes et al.
    Dorsal paired medial neurons, which are required for memory consolidation, promote sleep by inhibiting the excitation of mushroom body neurons.

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