2,863 results found
    1. Neuroscience

    Longitudinal stability of medial temporal lobe connectivity is associated with tau-related memory decline

    Quanjing Chen, Adam Turnbull ... Feng V Lin
    Phosphorylated tau was related to a loss of structural stability in medial temporal lobe connectivity, and this loss of stability moderated the relationship between phosphorylated tau accumulation and memory decline.
    1. Neuroscience

    Conduction velocity along a key white matter tract is associated with autobiographical memory recall ability

    Ian A Clark, Siawoosh Mohammadi ... Eleanor A Maguire
    A new magnetic resonance brain imaging measure reveals that variations in people’s ability to recall their past experiences may be related to the speed at which electrical signals travel along axons in the parahippocampal cingulum bundle.
    1. Neuroscience

    Transient acidosis while retrieving a fear-related memory enhances its lability

    Jianyang Du, Margaret P Price ... Michael J Welsh
    Activating ASIC channels in the amygdala makes a single reminder more effective at rendering consolidated fear memories labile and susceptible to modification.
    1. Neuroscience

    Long-term stability of cortical ensembles

    Jesús Pérez-Ortega, Tzitzitlini Alejandre-García, Rafael Yuste
    Spontaneous and visually evoked neuronal ensembles in mouse visual cortex can last for weeks, potentially supporting the long-lasting representation of perceptions and memories.
    1. Neuroscience

    A kinase-dependent feedforward loop affects CREBB stability and long term memory formation

    Pei-Tseng Lee, Guang Lin ... Hugo J Bellen
    Through an image and behavioral screen based on MiMIC technology, we identified a novel kinase, CG11221 renamed Meng-Po (MP), and showed that flies that lack MP in mushroom bodies can learn but cannot remember as MP is required for the protein stability of CREBB.
    1. Neuroscience

    Noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation

    Josué Haubrich, Matteo Bernabo, Karim Nader
    The overactivation of noradrenergic inputs to the amygdala during severe fear learning increases memory stability at the expense of lability, rendering the trace resistant to memory destabilization and reconsolidation.
    1. Immunology and Inflammation

    Natural Tr1-like cells do not confer long-term tolerogenic memory

    Koshika Yadava, Carlos Obed Medina ... Paul L Bollyky
    Natural Tr1-like cells do not form a functionally stable memory response to allergens, and this instability may limit efforts to re-establish tolerance by expanding Tr1.
    1. Neuroscience

    A prediction model of working memory across health and psychiatric disease using whole-brain functional connectivity

    Masahiro Yamashita, Yujiro Yoshihara ... Hiroshi Imamizu
    Human neuroimaging and machine learning reveals a generalizable relationship between brain connectivity and working memory ability across healthy populations and distinct psychiatric diagnoses.
    1. Neuroscience

    Minian, an open-source miniscope analysis pipeline

    Zhe Dong, William Mau ... Denise J Cai
    Minian is an open-source analysis pipeline for calcium imaging data that enhances usability with low memory demands and transparency with user-friendly interactive visualizations.
    1. Neuroscience

    The actin-modulating protein synaptopodin mediates long-term survival of dendritic spines

    Kenrick Yap, Alexander Drakew ... Thomas Deller
    Long-term imaging of dentate granule cells reveals that the presence of synaptopodin within large spines, rather than their size, conveys long-term stability to large spines.

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