Insulinergic neuromodulation of hedonic food processing predicts future weight management and improves with weight loss in older overweight dieters.

Heterozygous Nf1 knockout mice exhibit distinct dopaminergic phenotypes in vivo, as revealed by the genetically encoded dopamine sensor dLight1, patch clamp electrophysiology, optogenetics, and novel viral tools for morphological analysis.

A consistent pattern of consumption of Triticeae tribe grasses documented in the Danube Gorges of the Balkans since the Early Mesolithic might have facilitated a quick uptake of domesticated cereals due to a developed cultural taste and specific stone tool processing technology.

Neural confidence signals can take the role of reward signals and explain perceptual learning without external feedback as a form of internal reinforcement learning.

Inhibiting ventral tegmental dopamine neurons, or their inputs to nucleus accumbens, disrupts cue-motivated reward seeking in a manner that depends on the microstructure of behavior.

Molecular, laminar, and regional characterization in combination with classical and conditional tracing techniques reveal that medial prefrontal cortical neurons innervating the nucleus accumbens and the ventral tegmental area form distinct populations.

An implantable device based on organic electrochemical transistors is developed for quantitative mapping of neurotransmitter release across multiple brain regions, revealing a cross-talk between the mesolimbic and nigrostriatal dopaminergic pathways.

The molecular mechanisms by which midbrain dopamine neurons acquire the inhibitory neurotransmitter GABA for synaptic release are revealed.

Genetic analysis of Ntn1 in adult mouse midbrain neurons reveals its function in maintaining excitatory synapses, loss of Ntn1 function in inhibitory neurons is significantly detrimental to mesolimbic system function.