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    1. Neuroscience
    2. Computational and Systems Biology

    Visual information is broadcast among cortical areas in discrete channels

    Yiyi Yu, Jeffery N Stirman ... Spencer LaVere Smith
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    Morphogenetic degeneracies in the actomyosin cortex

    Sundar Ram Naganathan, Sebastian Fürthauer ... Stephan W Grill
    Distinct molecular functions contribute to the same material property at larger scales leading to degenerate functionality.
    1. Neuroscience

    Spatiotemporal organisation of human sensorimotor beta burst activity

    Catharina Zich, Andrew J Quinn ... Sven Bestmann
    Burst activity can be described in all three signal domains and sensorimotor beta burst activity propagates along two axes either parallel or perpendicular to the central sulcus.
    1. Neuroscience

    Functionally defined white matter of the macaque monkey brain reveals a dorso-ventral attention network

    Ilaria Sani, Brent C McPherson ... Winrich A Freiwald
    Primate attention is not limited to a dorsal fronto-parietal network, but includes a ventral temporal node and its dorso-ventral interactions with other attentional areas.
    1. Neuroscience

    Structured inhibitory activity dynamics in new virtual environments

    Moises Arriaga, Edward B Han
    Inhibitory interneuron activity is dynamically modulated in new environments while individual interneurons show consistent levels of activity modulation across multiple environments, suggesting functional specialization of inhibitory subnetworks.
    1. Computational and Systems Biology
    2. Neuroscience

    Myelin dystrophy impairs signal transmission and working memory in a multiscale model of the aging prefrontal cortex

    Sara Ibañez, Nilapratim Sengupta ... Christina M Weaver
    Biologically plausible levels of myelin dystrophy induce substantial working memory impairment in a computational model of brain aging across two spatial and temporal scales.
    1. Neuroscience

    Dissociation of impulsive traits by subthalamic metabotropic glutamate receptor 4

    Lukasz Piszczek, Andreea Constantinescu ... Wulf Haubensak
    Metabotropic glutamate receptors modulate impulse control by the subthalamic nucleus, dissociating trait impulsivity from basal ganglia motor function.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    The role of scaffold reshaping and disassembly in dynamin driven membrane fission

    Martina Pannuzzo, Zachary A McDargh, Markus Deserno
    Computational modeling of a dynamin-constricted membrane neck can rank proposed shape changes of the helical scaffold in terms of their fission aptitude and elucidate the associated pathways.
    1. Computational and Systems Biology

    Active contraction of microtubule networks

    Peter J Foster, Sebastian Fürthauer ... Daniel J Needleman
    Microtubule networks in frog egg extracts can spontaneously contract in a manner that can be quantitatively described by an active fluid model.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The physical dimensions of amyloid aggregates control their infective potential as prion particles

    Ricardo Marchante, David M Beal ... Wei-Feng Xue
    Size threshold and suprastructure formation are key parameters that control the infective potential of amyloid fibrils as prion particles.