3,611 results found
    1. Epidemiology and Global Health

    Quantifying antibody kinetics and RNA detection during early-phase SARS-CoV-2 infection by time since symptom onset

    Benny Borremans et al.
    A meta-analysis shows that seroconversion of antibodies against SARS-CoV-2 is not affected by disease severity and finds higher viral RNA detection probability in lower respiratory tract and fecal samples.
    1. Evolutionary Biology

    Plasticity and evolutionary convergence in the locomotor skeleton of Greater Antillean Anolis lizards

    Nathalie Feiner et al.
    A comparative and experimental research refutes the controversial hypothesis that plasticity played a major role in the convergent evolution of Anolis ecomorphs.
    1. Neuroscience

    Empathic pain evoked by sensory and emotional-communicative cues share common and process-specific neural representations

    Feng Zhou et al.
    Machine learning analyses reveal that the observation of acute pain inflictions and facial expressions of pain evoke shared pain-specific neural representations.
    1. Microbiology and Infectious Disease

    The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching

    Brittany L Carroll et al.
    In situ structures of the flagellar motors genetically docked in CCW and CW rotational states reveal major rearrangement that facilitates rotational switch in Vibrio alginolyticus..
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Poultry farmer response to disease outbreaks in smallholder farming systems in southern Vietnam

    Alexis Delabouglise et al.
    Longitudinal monitoring of poultry farms in southern Vietnam reveals that when outbreaks occur with symptoms similar to highly pathogenic avian influenza, farmers respond by sending their chickens to market early.
    1. Structural Biology and Molecular Biophysics

    Cadherin clusters stabilized by a combination of specific and nonspecific cis-interactions

    Connor J Thompson et al.
    A combined experimental and computational approach was developed to understand lateral interactions between membrane-bound proteins and used to quantify the contributions of specific and non-specific interactions to cadherin cis-binding kinetics.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Genetic mapping of etiologic brain cell types for obesity

    Pascal N Timshel et al.
    Unbiased computational integration of single-cell- and human genetics data shows that susceptibility to obesity is driven by a broad set of neuronal populations across the brain.
    1. Chromosomes and Gene Expression

    Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments

    Hajnalka L Pálinkás et al.
    Human genomic DNA contains uracil in the late replicating, constitutive heterochromatic regions, while treatment with drugs perturbing thymidylate biosynthesis shifts the uracil distribution pattern towards the euchromatin in UNG-inhibited cells.
    1. Computational and Systems Biology

    Removing unwanted variation with CytofRUV to integrate multiple CyTOF datasets

    Marie Trussart et al.
    CytofRUV is a computational algorithm that effectively enables batch effect reduction in multiple CyTOF batches with an adaptable normalisation method and an R-Shiny application with diagnostics plots.
    1. Microbiology and Infectious Disease

    The Mla pathway in Acinetobacter baumannii has no demonstrable role in anterograde lipid transport

    Matthew J Powers et al.
    An outer membrane vesicle pulse-chase assay demonstrates that the Acinetobacter baumannii Mla system is a retrograde lipid transporter.

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