Crowding and metabolites in a simulated cellular environment alter protein conformations, modulate interactions of functionally related proteins, and lead to significant dynamic heterogeneity.

Physical and chemical interactions with bacteria influence the life and death of Emiliania huxleyi, a bloom-forming micro-alga important in global biogeochemical cycles.

Metabolic division of labor in B. subtilis controls the extracellular environment.

The stability of metabolic autocatalytic cycles that are widespread in central metabolism limits the affinities of enzymes at flux branch points and explains excess expression of these enzymes.

Rewiring of transcriptional circuits can preserve a basic output yet alter almost all of the circuit's quantitative and qualitative features.

In a consumer-resource model obeying the physical requirement of flux conservation, metabolic competition between microbes yields consortia of cell types that collectively resist invasion via optimal use of resources.

Cognitive performance is supported by symbiotic metabolic and neuro-vascular responses in task-specific brain networks.

Metabolic labelling reveals complex proteome dynamics in tendon, with faster turnover of proteins in the glycoprotein-rich interfascicular matrix compared to the collagen-rich fascicular matrix.

A genome scale model of Brugia malayi metabolism illustrates a dynamic reliance on energy production pathways across its life cycle and identifies new drugs with experimentally supported anti-parasitic properties.

A user-friendly genetically-encoded fluorescent sensor of improved dynamic range is introduced to facilitate the study of mitochondrial metabolism and diversity.