Leaf-cutting ants use their fecal fluid to vector enzymes produced by their fungal symbiont to degrade plant biomass with a combination of degradation enzymes and Fenton chemistry.

17α-Estradiol, a life-span extending compound, signals through estrogen receptor α (ERα) in the liver and hypothalamus to elicit health benefits in a sex-specific manner.

A novel bacterial deubiquitinase with multiple chain types specificity regulates the association of ubiquitinated proteins on the phagosome of Legionella pneumophila.

Estrogen aggravates mammary involution through lysosome-mediated cell death, neutrophil recruitment via CXCR2 signalling, neutrophil-mediated inflammation and adipocyte repopulation.

Multicellular and socially aggregating prokaryotes contain previously undescribed, chaperone-based systems predicted to mediate defensive biological conflicts, several components of which are thematically similar antecedents of eukaryotic apoptosis pathways.

A novel IVDD mechanism that involves p16 is demonstrated and theoretical evidence is provided for effective methods to downregulate p16 and so reverse IVDD.

Stem cell-derived motor neurons with differential ALS vulnerability identified proteasome activity as a possible mechanism that explains their differential sensitivity.

Comprehensive scRNA-seq analysis of cardiac stromal cells in healthy and injured hearts reveals novel cell types and non-linear cell dynamics, providing new insights into cardiac inflammation, fibrosis and repair.

Penicillin induces bacterial cell lysis by altering cell surface polymer biogenesis to cause the misactivation of a cell wall degrading enzyme.

lncEGFL7OS is a lncRNA located at the EGFL7/miR-126 locus that is critical for angiogenesis in humans.