46 results found
    1. Neuroscience

    Science Forum: How failure to falsify in high-volume science contributes to the replication crisis

    Sarah M Rajtmajer, Timothy M Errington, Frank G Hillary
    An increased emphasis on falsification – the direct testing of strong hypotheses – will lead to faster progress in science by allowing well-specified hypotheses to be eliminated.
    1. Cancer Biology

    Reproducibility in Cancer Biology: Challenges for assessing replicability in preclinical cancer biology

    Timothy M Errington, Alexandria Denis ... Brian A Nosek
    A project to repeat experiments from high-impact papers in cancer biology encountered a series of challenges, many of which were caused by a lack of detail in the original papers.
  1. Composing reproducible manuscripts using R Markdown

    Chris Hartgerink explains how and why he uses R Markdown to write dynamic research documents.
  2. Webinar Report: The "science of science" - using meta-research to make research more transparent and reproducible

    Watch back as our panelists explore ways that you can use meta-research, or the science of science, to make research more transparent, rigorous and reproducible.
    1. Medicine
    2. Neuroscience

    Science Forum: Consensus-based guidance for conducting and reporting multi-analyst studies

    Balazs Aczel, Barnabas Szaszi ... Eric-Jan Wagenmakers
    Using multiple analysts to independently analyze the same dataset has the potential to explore and strengthen the robustness of results and conclusions in basic and applied research.
  3. Meta-Research: Investigating disagreement in the scientific literature

    Wout S Lamers, Kevin Boyack ... Dakota Murray
    An approach based on cue phrases can be used to identify instances of disagreement in scientific articles and compare the level of disagreement in various disciplines.
    1. Cancer Biology

    Reproducibility in Cancer Biology: Rethinking research into metastasis

    Peter Friedl
    The partial success of an attempt to repeat findings in cancer biology highlights the need to improve study designs for preclinical research into metastasis and the targeting of cancer cells.
    Version of Record
    Insight
    1. Cancer Biology

    Reproducibility in Cancer Biology: Pseudogenes, RNAs and new reproducibility norms

    George A Calin
    The partial success of a study to reproduce experiments that linked pseudogenes and cancer proves that understanding RNA networks is more complicated than expected.
    Version of Record
    Insight

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