Sarah M Rajtmajer, Timothy M Errington, Frank G Hillary
An increased emphasis on falsification – the direct testing of strong hypotheses – will lead to faster progress in science by allowing well-specified hypotheses to be eliminated.
Timothy M Errington, Alexandria Denis ... Brian A Nosek
A project to repeat experiments from high-impact papers in cancer biology encountered a series of challenges, many of which were caused by a lack of detail in the original papers.
Watch back as our panelists explore ways that you can use meta-research, or the science of science, to make research more transparent, rigorous and reproducible.
Using multiple analysts to independently analyze the same dataset has the potential to explore and strengthen the robustness of results and conclusions in basic and applied research.
An approach based on cue phrases can be used to identify instances of disagreement in scientific articles and compare the level of disagreement in various disciplines.
The partial success of an attempt to repeat findings in cancer biology highlights the need to improve study designs for preclinical research into metastasis and the targeting of cancer cells.
The partial success of a study to reproduce experiments that linked pseudogenes and cancer proves that understanding RNA networks is more complicated than expected.