15 results found
    1. Structural Biology and Molecular Biophysics

    Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector

    Matteo Allegretti et al.
    The structure of a large enzyme complex involved in methanogenesis was determined at high resolution by electron cryo-microscopy.
    1. Structural Biology and Molecular Biophysics

    De novo modeling of the F420-reducing [NiFe]-hydrogenase from a methanogenic archaeon by cryo-electron microscopy

    Deryck J Mills et al.
    The structure of a large hydrogenase complex involved in the production of methane by microbes has been determined with cryo-electron microscopy.
    1. Microbiology and Infectious Disease

    Post-translational thioamidation of methyl-coenzyme M reductase, a key enzyme in methanogenic and methanotrophic Archaea

    Dipti D Nayak et al.
    Post-translational installation of thioglycine in methyl-coenzyme M reductase in the methanogenic archaeon Methanosarcina acetivorans is mediated by the tfuA-ycaO locus and stabilizes the protein secondary structure near the active site.
    1. Neuroscience

    Brain-wide cellular resolution imaging of Cre transgenic zebrafish lines for functional circuit-mapping

    Kathryn M Tabor et al.
    A new resource of transgenic zebrafish lines facilitates precise targeting of neuronal cell-types within the brain, supported by online software for visualizing transgene expression patterns.
    1. Evolutionary Biology

    Membranes, energetics, and evolution across the prokaryote-eukaryote divide

    Michael Lynch, Georgi K Marinov
    The common view that the mitochondrion endowed eukaryotes with a boost in bioenergetic capacity above that in prokaryotes is inconsistent with a diversity of cellular features.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    An intracellular anion channel critical for pigmentation

    Nicholas W Bellono et al.
    Oculocutaneous albinism II (OCA2) contributes to a melanosome-specific anion channel that modulates organellar pH and is critical for melanin synthesis.
    1. Neuroscience

    An arbitrary-spectrum spatial visual stimulator for vision research

    Katrin Franke et al.
    Towards a community effort, we here present a flexible yet standardised visual stimulator design based on open hardware and software.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Microfluidic-based mini-metagenomics enables discovery of novel microbial lineages from complex environmental samples

    Feiqiao Brian Yu et al.
    Microfluidic-based mini-metagenomics enables the investigation of environmental microbial communities in high-throughput and with single-cell resolution, facilitating genome binning and quantification of function, abundance, and genome variation.
    1. Cell Biology
    2. Neuroscience

    Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system

    Gianluca Figlia et al.
    High PI3K-Akt-mTORC1 activity inhibits Schwann cell differentiation, while after onset of myelination, residual PI3K-Akt-mTORC1 activity promotes myelin growth.
    1. Evolutionary Biology

    A β-carotene-binding protein carrying a red pigment regulates body-color transition between green and black in locusts

    Meiling Yang et al.
    Body color change of locusts reveals a new 'palette effect' mechanism by which the red βCBP–β-carotene pigment complex acts as a switch to coordinate between black and green coloration.

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