Browse the search results

Page 2 of 37
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cell-free DNA as a potential biomarker of differentiation and toxicity in cardiac organoids

    Brian Silver, Kevin Gerrish, Erik Tokar
    Cardiac organoids have potential as a tool used for identifying cell-free DNA as biomarkers for toxicity and severity of exposure outcomes.
    1. Microbiology and Infectious Disease

    Total parasite biomass but not peripheral parasitaemia is associated with endothelial and haematological perturbations in Plasmodium vivax patients

    João L Silva-Filho, João CK Dos-Santos ... Fabio TM Costa
    Data exploring host and parasite signatures in the peripheral blood indicate that total parasite biomass is a better predictor of P. vivax-induced host responses and pathogenesis than peripheral parasitemia.
    1. Genetics and Genomics

    Reprogramming of translation in yeast cells impaired for ribosome recycling favors short, efficiently translated mRNAs

    Swati Gaikwad, Fardin Ghobakhlou ... Alan G Hinnebusch
    A mutant impaired for ribosome recycling exhibits translational reprogramming wherein strong mRNAs outcompete weak mRNAs, also observed when preinitiation complexes are diminished by eIF2α phosphorylation or 40S ribosomal subunit depletion.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females

    Bretta Hixson, Xiao-Li Bing ... Nicolas Buchon
    RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.
    1. Developmental Biology
    2. Evolutionary Biology

    Insect metamorphosis is regulated differently between sexes by members of a microRNA cluster

    Chade Li, Ki Kei Chan ... Jerome HL Hui
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Microbiology and Infectious Disease

    Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface

    Liheng Yang, Eleanor C Semmes ... Carolyn B Coyne
    Organoids developed from matched human placental tissue define differences in antiviral signaling between cell types comprising the maternal-fetal interface.
    1. Medicine
    2. Microbiology and Infectious Disease

    HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity

    Karen Giménez-Orenga, Eva Martín-Martínez ... Elisa Oltra
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology

    Syncytin-mediated open-ended membrane tubular connections facilitate the intercellular transfer of cargos including Cas9 protein

    Congyan Zhang, Randy Schekman
    A human endogenous fusogen, syncytin, which facilitates placental cell-cell fusion during early embryonic development, mediates the formation of open-ended membrane tubular connections between other cell types that efficiently promotes the intercellular transfer of cytoplasmic cargos including Cas9 protein and organelles.
    1. Developmental Biology
    2. Genetics and Genomics

    Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control

    Ananya Chakravarti, Heshani N Thirimanne ... Brian R Calvi
    Drosophila p53 protein isoforms function during oogenesis to ensure the integrity of the transmitted genome, a function that is conserved to humans.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations

    Basel Maher Al-Barghouthi, Will T Rosenow ... Charles R Farber
    Systems genetics approaches identify potentially causal bone mineral density genes.