2,965 results found
    1. Plant Biology

    Antimicrobial peptide expression in a wild tobacco plant reveals the limits of host-microbe-manipulations in the field

    Arne Weinhold et al.
    The attempt to manipulate a microbiome in planta to study the ecological consequences under field conditions leaves plants and their microbes surprisingly unimpressed.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A natural variant of the essential host gene MMS21 restricts the parasitic 2-micron plasmid in Saccharomyces cerevisiae

    Michelle Hays et al.
    A novel assay to measure 2-micron stability together with a survey of natural variation among Saccharomyces cerevisiae strains reveals novel means by which yeasts can combat the parasitic 2-micron plasmids.
    1. Immunology and Inflammation

    Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit

    Yasunobu Arima et al.
    A link between chronic stress and organ dysfunction is explained by the gateway reflex, in which brain micro-inflammation at specific vessels establishes a new neural pathway to induce fatal organ failure particularly in gastrointestine and heart.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structure of catalase determined by MicroED

    Brent L Nannenga et al.
    Building on previous work (Shi et al., 2013), we have used MicroED to determine the structure of catalase at 3.2 Å resolution from a single crystal.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs

    Leah Guthrie et al.
    A network of the gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs and supports the generation of mechanistic hypotheses of microbiome metabolic phenotypes that shape human biology.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    MicroCT-based phenomics in the zebrafish skeleton reveals virtues of deep phenotyping in a distributed organ system

    Matthew Hur et al.
    Deep skeletal phenotyping in adult zebrafish reveals enhanced sensitivity of phenomic patterns in discriminating mutant populations.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Three-dimensional electron crystallography of protein microcrystals

    Dan Shi et al.
    A new electron diffraction technique called MicroED allows protein structures to be determined from three-dimensional microcrystals.
    1. Physics of Living Systems
    2. Microbiology and Infectious Disease

    Cyanobacteria use micro-optics to sense light direction

    Nils Schuergers et al.
    The cells of a cyanobacterium act as spherical micro-lenses, allowing the cell to see a light source and move towards it.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Extensive transmission of microbes along the gastrointestinal tract

    Thomas SB Schmidt et al.
    Microbial populations are continuous along the gastrointestinal tract, with increased transmission in colorectal cancer and rheumatoid arthritis patients.
    1. Immunology and Inflammation

    Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

    Jose U Scher et al.
    The sequencing of microbial genomes reveals that the presence of a particular microbial species in the gut may increase the risk of the autoimmune disease rheumatoid arthritis.

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