743 results found
  1. October 2013

    Episode 5: October 2013

    In this episode we hear about how chimpanzees use conceptual metaphors, hyperactive sperm, the use of bacteria to estimate the time of death, stem cells and smoking, and a new type of bacteria.
    1. Evolutionary Biology
    2. Epidemiology and Global Health
    3. Microbiology and Infectious Disease
    4. Genetics and Genomics

    Evolutionary Medicine: A Special Issue

    Edited by George H Perry et al.
    eLife is pleased to present a Special Issue to highlight recent advances in the growing and increasingly interdisciplinary field of evolutionary medicine.
  2. November 2013

    Episode 6: November 2013

    In this episode we hear about using electrons for protein crystallography, a receptor for carbon dioxide, arthritis, how the brain responds to a missing hand, and the best shape for whiskers.
  3. A series of articles on the philosophy of biology

    Philosophy of Biology

    Edited by Helga Groll
    A series of articles offering philosophical perspectives on the life sciences.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Reactive oxygen species oxidize STING and suppress interferon production

    Lili Tao et al.
    Redox modification of STING represents a novel target for interferon regulation and control of herpesvirus replication.
    1. Genetics and Genomics
    2. Neuroscience

    An adipokine feedback regulating diurnal food intake rhythms in mice

    Anthony H Tsang et al.
    Adiponectin signaling integrates metabolic state information to regulate circadian clock function in hypothalamic appetite regulating centers, food intake rhythms, and body weight.
    1. Genetics and Genomics

    A regulatory pathway that selectively up-regulates elongasome function in the absence of class A PBPs

    Yesha Patel et al.
    Balanced peptidoglycan synthesis requires regulators, including sigma-I and WalKR, that coordinate the diffusive action of class A PBPs and the directional motion of the MreB-directed elongasome.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Emergence and diversification of a host-parasite RNA ecosystem through Darwinian evolution

    Taro Furubayashi et al.
    In an in vitro RNA replication system, an RNA spontaneously diversifies and continuously evolves through coevolution with parasitic entities.
    1. Immunology and Inflammation

    Dithranol targets keratinocytes, their crosstalk with neutrophils and inhibits the IL-36 inflammatory loop in psoriasis

    Theresa Benezeder et al.
    Targeting the differentiation regulators and/or AMPs of keratinocytes, rather than targeting immune cells, may be an alternative approach for topical anti-psoriatic treatment, an area with high need for new drugs.
    1. Microbiology and Infectious Disease

    Dominant Vibrio cholerae phage exhibits lysis inhibition sensitive to disruption by a defensive phage satellite

    Stephanie G Hays, Kimberley D Seed
    Genetic and molecular analyses identify and characterize an evolutionary battle over lysis timing wherein a bacteriophage delays lysis through lysis inhibition while a defensive phage satellite accelerates lysis.

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