A 2-year field experiment reveals that plant secondary metabolites can be harnessed to increase crop productivity through plant-soil feedbacks under agronomically realistic conditions.
Gut microbiota from young mice can alleviate gout and hyperuricemia in aged mice, further revealing that the metabolic product butyrate derived from the gut microbiota exerts similar therapeutic effects.
Vera Vollenweider, Karoline Rehm ... Rolf Kümmerli
Iron-chelating pyoverdines from environmental Pseudomonas spp. show promising antibacterial activity against key human pathogens through the induction of iron starvation, while associated toxicity for host systems remains low.
Metabolomics analysis identified potential neuroactive metabolites, issued from food and microbial fermentation, that are linked to symptoms of depression, anxiety and alcohol craving.
Gut microbiota reshaped by myostatin gene variation has a positive effect on skeletal muscle growth by activating GPR43 through valeric acid, as a metabolite of gut microbiota.
Opportunistic bacteria modulate their lifestyle from coexistence to pathogenicity by perceiving the physiological state of their algal host through sensing of algal secreted metabolites.
A basidiomycete yeast closely related to fungal smuts is an antagonistic microbe in the Arabidopsis leaf phyllosphere that inhibits infection by Albugo laibachii via a GH25 hydrolase with lysozyme activity.
Ahmed A Shibl, Michael A Ochsenkühn ... Shady A Amin
Characterization of the molecular mechanisms that enable azelaic acid, a secondary metabolite produced by photosynthetic organisms, to promote or inhibit different bacterial populations.
Maria Cristina Stroe, Tina Netzker ... Axel A Brakhage
A silent gene cluster of the fungus Aspergillus fumigatus is activated by a bacterium and leads to the production of a novel spore germination inhibitor targeting the inducing bacterium.
