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    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending

    Aleksandra Bebel, Ezgi Karaca ... Orsolya Barabas
    DNA-bound crystal structures of an essential Xer site-specific recombinase from the bacterium Helicobacter pylori reveal how large conformational changes initiate the untangling of chromosomes upon cell division.
    1. Microbiology and Infectious Disease

    A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates

    Philip W Fowler, Carla Wright ... The CRyPTIC Consortium
    A crowd of inexperienced volunteers can reproducibily and accurately measured how effective a panel of antibiotics are in treating a M. tuberculosis sample.
  3. Jennifer Tsang

    Interview: Blogging and being social

    Jennifer Tsang describes how her career path led her from microbiology to science communication and marketing.
    1. Microbiology and Infectious Disease

    Droplet-based high-throughput cultivation for accurate screening of antibiotic resistant gut microbes

    William J Watterson, Melikhan Tanyeri ... Savaş Tay
    High-throughput droplet-based cultivation of gut microbes reduces biases of traditional cultivation strategies and thereby enables detection of difficult-to-culture organisms, which is required in applications such as antibiotic screening.
    1. Computational and Systems Biology

    Structural assembly of the bacterial essential interactome

    Jordi Gómez Borrego, Marc Torrent Burgas
    A new study reveals structural details of the bacterial essential interactome, opening new avenues for antibiotic discovery.
    1. Cell Biology

    A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals

    Rosanna A Alegado, Laura W Brown ... Nicole King
    The development of colonies of cells in choanoflagellates, water-dwelling organisms that feed on bacteria, is triggered by the presence of very low concentrations of a lipid molecule produced by certain types of bacteria.

  7. Professional development: an interview with Maria Fernandes

    While doing a PhD in Pharmacology at King’s College London (KCL), Maria Fernandes seized a number of opportunities – setting up the KCL Pharmacological Society, organising events and sitting on committees – to gain enough experience to move into a career outside of research. She is now the Professional Development Manager at the Microbiology Society.
    1. Microbiology and Infectious Disease

    Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations

    Karthik Hullahalli, Marinelle Rodrigues, Kelli L Palmer
    Conflicts between CRISPR-Cas systems and antibiotic resistance plasmids can be exploited to selectively eliminate antibiotic resistance from Enterococcus faecalis populations.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Glycan-based shaping of the microbiota during primate evolution

    Sumnima Singh, Patricia Bastos-Amador ... Miguel P Soares
    Ggta1 deletion in mice shapes and reduces the microbiota pathogenicity and probably contributed to the natural selection of GGTA1 loss-of-function mutations in the ancestral primates that gave rise to humans.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3

    Radim Osicka, Adriana Osickova ... Peter Sebo
    A toxin produced by the bacterium Bordetella pertussis preferentially binds to non-activated integrin complement receptor 3 outside of its ligand-binding I-domain and efficiently blocks downstream signaling of the integrin through elevation of cytosolic cAMP.
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