147 results found
    1. Neuroscience

    Aberrant sorting of hippocampal complex pyramidal cells in type I lissencephaly alters topological innervation

    James A D'Amour et al.
    The loss of lamination in mammalian brain structures under cellular heterotopia carries with it non-uniform ramifications for the various components of the canonical CA1 microcircuitry.
    1. Neuroscience

    Apical length governs computational diversity of layer 5 pyramidal neurons

    Alessandro R Galloni et al.
    Layer 5 pyramidal neurons vary substantially in dendritic excitability between primary and secondary visual cortex, likely due to a counterintuitive amplifying effect of long apical dendrites.
    1. Neuroscience

    Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity

    Christopher W Thomas et al.
    The global sleep homeostatic process tracks sleep-wake history by integrating local cortical neuronal activity over time and space, rather than directly reflecting changes in specific homeostatically regulated physiological variables.
    1. Neuroscience

    Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells

    Ramesh Chittajallu et al.
    Similar to their mouse counterparts, human neurogliaform cells that comprise a specialized from of inhibitory neuron, possess the ability to modulate their intrinsic excitability in response to ongoing network activity.
    1. Neuroscience

    Circuits that encode and guide alcohol-associated preference

    Kristin M Scaplen et al.
    Alcohol modifies dopaminergic microcircuits required for acquisition and expression of sensory memories in Drosophila resulting in a shift in behavioral response from malleable to inflexible.
    1. Neuroscience

    Complexity of frequency receptive fields predicts tonotopic variability across species

    Quentin Gaucher et al.
    The A1 of ferrets and mice show similar tonotopic organizations, with neurons preferring a single frequency being more precisely organized into a tonotopic map than multipeaked neurons.
    1. Neuroscience

    Distinct spatiotemporal mechanisms underlie extra-classical receptive field modulation in macaque V1 microcircuits

    Christopher A Henry et al.
    The multiple component mechanisms of extra-classical receptive field modulation, with distinct dynamics, discovered in the monkey visual cortex have important implications for understanding contextual perceptual processing.
    1. Neuroscience

    The sifting of visual information in the superior colliculus

    Kyu Hyun Lee et al.
    The superior colliculus reveals hallmarks of sophisticated visual computation, including selectivity, invariance, and stimulus-specific habituation to behaviorally relevant stimuli.
    1. Neuroscience

    Recurrent circuit dynamics underlie persistent activity in the macaque frontoparietal network

    Eric Hart, Alexander C Huk
    Simultaneous recordings of neural ensembles in both the frontal and parietal cortices reveal how persistent activity can be maintained in the primate brain during visuospatial working memory.
    1. Neuroscience

    Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input

    Zohre Azimi et al.
    Serotonergic input to visual cortex controls ongoing and evoked activity in a separable manner via distinct receptor pathways.

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