13 results found
    1. Neuroscience

    Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data

    Pengcheng Zhou et al.
    A new open-source computational toolbox for processing in vivo microendoscopic calcium imaging data performs signal demixing and denoising much more accurately than previously available methods, significantly improving the utility of this imaging modality.
    1. Neuroscience

    High-throughput synapse-resolving two-photon fluorescence microendoscopy for deep-brain volumetric imaging in vivo

    Guanghan Meng et al.
    Improved two-photon fluorescence microendoscopy enables volumetric imaging of synapses and neurons in deep brain structures in vivo.
    1. Neuroscience

    Extended field-of-view ultrathin microendoscopes for high-resolution two-photon imaging with minimal invasiveness

    Andrea Antonini et al.
    Aberration correction using 3D microprinting in ultrathin microendoscopes allows two-photon imaging of large neuronal networks with homogeneously high spatial resolution and minimal invasiveness in the deep mouse brain.
    1. Neuroscience

    A machine-vision approach for automated pain measurement at millisecond timescales

    Jessica M Jones et al.
    Development of a fully automated pain scale using machine learning tools in computational neuroethology and creation of new software, reveals a robust circuit-dissection compatible platform for objective pain measurement.
    1. Neuroscience

    Unsupervised discovery of temporal sequences in high-dimensional datasets, with applications to neuroscience

    Emily L Mackevicius et al.
    Building on simple unsupervised matrix factorization techniques, the seqNMF algorithm successfully recovers neural sequences in a wide range of simulated and real datasets.
    1. Neuroscience

    Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle

    Heng Zhou et al.
    Dynamic calcium activity in the hippocampus changes markedly across behavioral and physiological states and depends on muscarinic acetylcholine receptor activation.
    1. Neuroscience

    Hippocampal ensemble dynamics timestamp events in long-term memory

    Alon Rubin et al.
    Temporally close events share a common timestamp regardless of the spatial context in which they occur.
    1. Neuroscience

    CaImAn an open source tool for scalable calcium imaging data analysis

    Andrea Giovannucci et al.
    CaImAn is an open-software package that equips the neuroscience community with a set of turnkey, fast and scalable solutions to pre-processing problems arising in single cell calcium imaging data analysis.
    1. Neuroscience

    Dynamic encoding of social threat and spatial context in the hypothalamus

    Piotr Krzywkowski et al.
    Threat and context-responsive neurons in the ventromedial hypothalamus are reshaped by experience to drive social avoidance.
    1. Neuroscience

    The amygdala instructs insular feedback for affective learning

    Dominic Kargl et al.
    Hierarchical information flow in a cortico-limbic loop between the insular cortex, central amygdala and the cholinergic basal forebrain links bodily states with environmental stimuli to guide fear and reward behavior.

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