80 results found
    1. Medicine

    Gamma Knife Stereotactic radiotherapy combined with tislelizumab as later-line therapy in pMMR/MSS/MSI-L metastatic colorectal cancer: A Phase II Trial Analysis

    Yiran Zhang, Hanyang Guan ... Jinghua Pan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Cancer Biology

    Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer

    Yue Zhang, Hanbing Wang ... Jia Wei
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cancer Biology

    NOLC1 Suppresses Immuno-chemotherapy by Inhibiting p53-mediated Ferroptosis in Gastric Cancer

    Shengsheng Zhao, Ji Lin ... Weijian Sun
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Cancer Biology
    2. Cell Biology

    Bestrophin-4 relays HES4 and interacts with TWIST1 to suppress epithelial-to-mesenchymal transition in colorectal cancer cells

    Zijing Wang, Bihan Xia ... Jilin Yang
    The inhibition of colorectal cancer (CRC) proliferation, migration, and invasion is attributed to BEST4, which exhibits epistasis over Hes4 in the downregulation of Twist1 and consequent suppression of epithelial-to-mesenchymal transition in CRC.
    1. Cell Biology
    2. Cancer Biology

    N6-methyladenosine in DNA promotes genome stability

    Brooke A Conti, Leo Novikov ... Mariano Oppikofer
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cancer Biology

    The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization

    Thi Mong Quynh Pham, Thanh Nhan Nguyen ... Le Son Tran
    The integration of pHLA binding and pHLA-TCR analysis effectively improves the precision of insilico neoantigen prioritization, potentially enhancing personalized immunotherapies for colorectal cancer.
    1. Computational and Systems Biology
    2. Cancer Biology

    Is tumor mutational burden predictive of response to immunotherapy?

    Carino Gurjao, Dina Tsukrov ... Leonid A Mirny
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Biochemistry and Chemical Biology

    Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

    Nelson García-Vázquez, Tania J González-Robles ... Sharon Kaisari
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cancer Biology
    2. Medicine

    Insights into metabolic heterogeneity of colorectal cancer gained from fluorescence lifetime imaging

    Anastasia D Komarova, Snezhana D Sinyushkina ... Marina V Shirmanova
    The level of heterogeneity of cellular energy metabolism increases with model complexity and is the highest in patients' tumors, which can be observed and quantified using FLIM of NAD(P)H.
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape

    Ashley L Cook, Surojit Sur ... Nicolas Wyhs
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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