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    1. Developmental Biology
    2. Genetics and Genomics

    Cell competition removes segmental aneuploid cells from Drosophila imaginal disc-derived tissues based on ribosomal protein gene dose

    Zhejun Ji et al.
    Cell competition is an important mechanism selecting against aneuploid cells.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

    Ruben Soto-Acosta et al.
    The Zika virus subgenomic flaviviral RNA binds to and inhibits the fragile X mental retardation protein, a novel Zika virus restriction factor.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation

    Ceri A Fielding et al.
    The human cytomegalovirus US12 gene family work co-operatively to degrade large numbers of immune ligands and prevent recognition by natural killer cells.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Mitosis: Checkpoint proteins come under scrutiny

    Maria Mora-Santos, Jonathan BA Millar
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters

    Ryo Nabeshima et al.
    Fam60a, a component of the Sin3a complex, is required for embryonic development and regulates methylation at a subset of gene promoters.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Kinetochore-independent chromosome segregation driven by lateral microtubule bundles

    Christina C Muscat et al.
    Chromosomes in C. elegans female reproductive cells segregate through motor-driven movement along lateral microtubule bundles.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    An integrative transcriptomic atlas of organogenesis in human embryos

    Dave T Gerrard et al.
    Integrating human embryonic transcriptomes from 15 sites during organogenesis identifies novel expression signatures linked to congenital disorders and a new programme of non-coding gene expression.
    1. Chromosomes and Gene Expression

    Gene regulation: A transcriptional switch controls meiosis

    A Elizabeth Hildreth, Karen M Arndt
    A key protein involved in the segregation of meiotic chromosomes is produced 'just in time' by the regulated expression of two mRNA isoforms.
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    1. Cell Biology

    A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1

    Natalia Felipe-Medina et al.
    Genetic and biochemical analysis reveal a variant in HSF2BP causing POI and C19ORF57/BRME1 as an interactor and stabilizer of HSF2BP by forming a complex with BRCA2, RAD51, RPA and PALB2.