1,243 results found
  1. May 2016

    Episode 29: May 2016

    In this episode we hear about parasitic worms, dog tumours, epilepsy, DNA sequencing classes and social behaviour in mice.
    1. Evolutionary Biology
    Paleontology

    Paleontology: A Collection of Articles

    Edited by Ian Baldwin et al.
    eLife has published papers on topics as diverse as paleoproteomics, ancient insects and the discovery of a new hominin species.
  2. Episode 44: January 2018

    In this episode, we hear about self-esteem, a new genus of extinct horse, the future of biological engineering, mosquito trackers, and sperm competition in salmon.
  3. Episode 46: March 2018

    In this episode, we hear about autism, insulin resistance, Sci-Hub, coping with low levels of oxygen, and how the brain responds to blindness.
    1. Cancer Biology
    2. Immunology and Inflammation

    Discovery and Translation of Cancer Immunology: A Special Issue

    Edited by Jeffrey Settleman et al.
    eLife is pleased to present a Special Issue to highlight recent advances in the mechanistic understanding of the immune response to cancer cells.
    1. Biochemistry and Chemical Biology

    The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers

    Purnima Klingauf-Nerurkar et al.
    The GTPase Nog1 orchestrates stalk assembly, peptidyl transferase centre maturation and polypeptide exit tunnel quality control.
    1. Microbiology and Infectious Disease

    Mechanisms of virus dissemination in bone marrow of HIV-1–infected humanized BLT mice

    Mark S Ladinsky et al.
    Large-volume light microscopy combined with higher-resolution electron tomography revealed the spatial distribution of virus-producing cells and highlighted mechanisms of HIV-1 dissemination in bone marrow from a small animal model.
    1. Cell Biology
    2. Neuroscience

    Transverse tubule remodeling enhances Orai1-dependent Ca2+ entry in skeletal muscle

    Antonio Michelucci et al.
    Structural and functional analyses show that transverse tubule association with stacks of sarcoplasmic reticulum enhances Orai1-dependent Ca2+ entry to replenish Ca2+ stores, maintain Ca2+ release, and maximize force during exercise.
    1. Biochemistry and Chemical Biology
    2. Physics of Living Systems

    Optical estimation of absolute membrane potential using fluorescence lifetime imaging

    Julia R Lazzari-Dean et al.
    Fluorescence lifetime imaging microscopy, paired with fluorescent, voltage-sensitive dyes, provides a method for measuring and quantifying membrane potentials of living cells.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery

    Robin A Corey et al.
    How the process of protein folding may be controlled by the Sec machinery to assist protein transport across membranes.

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