An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.
It is of significance in identifying temperature sensitive brain regions in brain energy metabolism, as which might provide potential targetable sites in the treatment of brain lipid metabolism-associated neurological disorders.
A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation mechanisms.
