Prefrontal cortex plays a leading role in sequential decisions compared to posterior parietal cortex and relies on nonlinear integration of sensory and mnemonic information for decision formation.

Engagement in auditory detection task leads to selective enhancement of task relevant information by neural populations in higher order auditory cortex.

The evidence of subspace computation in the lateral prefrontal cortex provides insights into the neural mechanisms underlying cognitive flexibility and interference between different cognitive processes.

A new data analysis tool provides a concise way of visualizing neural data that summarizes all the relevant features of the population response in a single figure.

Firing rate nonlinearity recovers linear decodability of orientation information from simple cells of the primary visual cortex under uncertainty of nuisance parameters phase and spatial frequency.

The structure-based design established a new approach to control pathway-selective activation of opioid receptors, resulting in new dual MOR/KOR G-protein biased agonist analgesics with attenuated liabilities.

Comparison of feature encoding and top-down cognitive signals gives insight into the role of parietal cortex in mediating decision making.

Purified Pannexin 1 channels activated by caspase cleavage in proteoliposomes reconstitute a permeation pathway for intercellular signaling molecules important in inflammation and cell clearance.

Neuronal recordings reveal complex, heterogeneous inputs to face-selective neurons, suggesting that inferotemporal neurons do not represent objects in isolation, but are also sensitive to object relationships that reflect environmental regularities.