1,990 results found
    1. Neuroscience

    Representational untangling by the firing rate nonlinearity in V1 simple cells

    Merse E Gáspár et al.
    Firing rate nonlinearity recovers linear decodability of orientation information from simple cells of the primary visual cortex under uncertainty of nuisance parameters phase and spatial frequency.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Virology: Pushing the envelope

    Julia H Wildschutte, John M Coffin
    Primates have co-opted a viral gene to produce an envelope protein that prevents infection by the HERV-T virus and likely contributed to the extinction of this virus.
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    1. Biochemistry and Chemical Biology

    Intracellular Organization: Getting ready for DNA duplication

    Nina Y Yao, Michael E O'Donnell
    The discovery of a biomolecular condensate involved in DNA replication has wide ranging implications.
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    1. Human Biology and Medicine

    Science Forum: RIPOSTE: a framework for improving the design and analysis of laboratory-based research

    Nicholas GD Masca et al.
    The RIPOSTE framework has been developed to support early and regular discussions between scientists and statisticians in order to improve the design, conduct and analysis of laboratory studies.
    1. Neuroscience

    Functional clustering of dendritic activity during decision-making

    Aaron Kerlin et al.
    In motor cortex pyramidal neurons, diverse task-related signals are distributed throughout the dendritic arbor and compartmentalized by dendritic distance and branching.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit

    Ching-Ju Tsai et al.
    The structure of a light-sensitive G protein-coupled receptor in complex with a Gi-protein heterotrimer provides a structural foundation for the role of the receptor C-terminal tail in scaffolding and signaling.
    1. Neuroscience

    Population response magnitude variation in inferotemporal cortex predicts image memorability

    Andrew Jaegle et al.
    Population response magnitude predicts how well an image will be remembered, in both monkey inferotemporal cortex and neural networks trained to categorize objects.
    1. Human Biology and Medicine

    Stimulation of Piezo1 by mechanical signals promotes bone anabolism

    Xuehua Li et al.
    Mechanical stimuli activate Piezo1 in osteoblast lineage cells and thereby promote bone formation in part via Wnt1.
    1. Immunology and Inflammation

    The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets

    Takuya Koike et al.
    Unveiling a mechanism for the fate decision of B-cell differentiation into two functionally distinct memory B cell subsets.

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