1,030 results found
    1. Computational and Systems Biology
    2. Neuroscience

    T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells

    Marcel Beining et al.
    T2N, a novel interface between Matlab, TREES toolbox and NEURON, was used to generate compartmental models that reproduce the electrophysiology of dentate granule cells over a multitude of species, experimental conditions and developmental stages.
    1. Microbiology and Infectious Disease

    Stochastic variation in the initial phase of bacterial infection predicts the probability of survival in D. melanogaster

    David Duneau et al.
    An analysis of within-host bacterial proliferation reveals that minor "stochastic" variation in the ability of the innate immune response to control bacterial growth early on can result in either survival or death of the host.
    1. Microbiology and Infectious Disease

    Host Defense: Are we immune by chance?

    Andrea L Graham, Ann T Tate
    The sooner the immune system launches, the greater the chances the host has of survival.
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    1. Stem Cells and Regenerative Medicine

    Organoids: Synthetic scaffolds help airway cells reach maturity

    Marko Z Nikolić, Emma L Rawlins
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    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Point of View: Looking back and looking forward at Janelia

    Gerald M Rubin, Erin K O'Shea
    The Janelia Research Campus opened its doors 12 years ago: we describe the philosophy underpinning Janelia, the lessons learned, and plans for the future.
    1. Cell Biology
    2. Computational and Systems Biology

    Signaling Systems: Transferring information without distortion

    Steven S Andrews et al.
    Despite employing diverse molecular mechanisms, many different cell signaling systems avoid losing information by transmitting it in a linear manner.
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    1. Developmental Biology

    Addressing the ethical issues raised by synthetic human entities with embryo-like features

    John Aach et al.
    Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Chromatin: Assembly, remodelled

    Karim Bouazoune, Robert E Kingston
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    1. Human Biology and Medicine

    Tissue Engineering: Muscling in on the third dimension

    Mohsen Afshar Bakooshli, Penney M Gilbert
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