A circuit within the nucleus accumbens that exists during a specific developmental window through early adolescence male rats may serve as a substrate that underlies heightened reward seeking in this population.

Primary endothelial cell cultures contain markedly heterogeneous cell subtypes that exhibit distinct molecular responses to disease-relevant exposures.

Functional imaging of individual sensory afferents that innervate the cranial meninges in a mouse migraine model reveals heightened responsiveness to movement-related meningeal deformations that may underlie headache.

Cst7, a gene coding for protein cystatin F, is expressed by microglia in neurodegenerative disease models and mediates sex-dependent effects on microglial endolysosomal function and disease pathology.

Major neuron classes are activated when the fly walks, whether it chooses or is forced to do so.

Giant neuron derived vesicles called exophers are processed by phagocytosis in neighboring skin cells, and the phagocytic interaction promotes exopher production.

Behavioral and in vivo imaging analysis in the fly suggests that mating-related sensory experience regulates female odor perception and expression of choice behavior through a dopamine-gated learning circuit.

A novel mechanism describes how tonic activation of nicotinic acetylcholine receptors can modulate the timing of striatal output by priming feedforward inhibition.