Calcium response profiling of large populations of enteric neurons reveals hard-wired neural circuits that reflect the motility program portfolio of the intestinal region they occupy.
Electrophysiological recording and optogenetic manipulation approaches reveal that a multisensory bottom-up SC-LP-A1 pathway plays a role in contextual and cross-modality modulation of auditory cortical processing.
Toxoplasma gondii formins have several non-overlapping roles including generating an apico-basal flux of F-actin that is controlled by phosphorylation and methylation and is essential for motility.
Hydrodynamic and steric interactions slow vesicle mobility and are predicted to ultimately limit vesicle supply to the active zone during sustained high-frequency signalling at a central synapse.
Human mobility drives malaria importation within countries and threatens elimination interventions, but can be measured using new approaches that combine parasite genetics, mobile phone data, travel surveys and models.
Combining parasite genetic and human mobility data can provide detailed information on local and cross-border connectivity, allowing programs to strengthen local and regional coordination for successful elimination of malaria.