The global ensemble forecasting niche modelling of 11 vector competent triatomine species revealed climatic suitable regions outside their native distribution including the cosmopolitan vector Triatoma rubrofasciata.
Structural models of the chromatin remodeling enzyme Chd1 in solution and when bound to chromatin indicate that conformational changes to both the enzyme and the nucleosome occur upon nucleotide dependent engagement.
Flow-dependent remodeling of blood vessels is critical for normal physiology and for recovery from arterial blockage in disease; understanding its cellular mechanisms may lead to the development of treatments for patients that are deficient in this process following myocardial infarction or other vascular diseases.
Lutheran is a novel marker for classification of bile duct remodeling in distinct liver injury, and an interesting functional molecule for investigating the nature of liver stem/progenitor cells during regeneration.
Clonal tracing in vivo and quantitative modeling in silico reveal a unique mode of tissue growth and structural remodeling of the biliary system, providing an insight into the cellular basis for robust liver regeneration.
Neural crest cells differentiated from patient-derived cells with mutations in the chromatin remodeler CHD7 show defective delamination, migration and motility in vitro, and defective migration in chick embryos.