2,997 results found
    1. Cell Biology
    2. Developmental Biology and Stem Cells

    Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract

    Jianjun Sun, Allan C Spradling
    Secretory cells in the fruit fly reproductive tract produce secretions that control ovulation through a conserved mechanism that could provide insights into ovarian cancer.
    1. Developmental Biology and Stem Cells

    The zinc-finger transcription factor Hindsight regulates ovulation competency of Drosophila follicles

    Lylah D Deady et al.
    Hindsight/RREB-1 plays a conserved role in follicle maturation and ovulation by sequential upregulation of matrix metalloproteinase and adrenergic receptor in follicle cells.
    1. Genomics and Evolutionary Biology

    Minimal-assumption inference from population-genomic data

    Daniel B Weissman, Oskar Hallatschek
    The coalescent history of a population can be learned just from the present genomic diversity, without having detailed prior knowledge of the pattern of recombination or the forces driving coalescence.
    1. Neuroscience

    Demixed principal component analysis of neural population data

    Dmitry Kobak et al.
    A new data analysis tool provides a concise way of visualizing neural data that summarizes all the relevant features of the population response in a single figure.
    1. Neuroscience

    Mouse V1 population correlates of visual detection rely on heterogeneity within neuronal response patterns

    Jorrit S Montijn et al.
    Heterogeneity of neural responses in mouse cortex correlates better with visual detection than mean population activity.
    1. Biochemistry
    2. Biophysics and Structural Biology

    Allosteric modulation in monomers and oligomers of a G protein-coupled receptor

    Rabindra V Shivnaraine et al.
    Allosteric modulation in the M2 muscarinic receptor derives from a mix of interactions within and between the protomers of an oligomer.
    1. Neuroscience

    Paradoxical response reversal of top-down modulation in cortical circuits with three interneuron types

    Luis Carlos Garcia del Molino et al.
    Computational simulations and mathematical derivations reveal why the response of neural populations to external modulation is sometimes reversed with respect to what intuition would lead to believe in cortical circuits with multiple types of inhibitory neurons.
    1. Cell Biology
    2. Developmental Biology and Stem Cells

    Cancer: Evolution, ovulation and cancer

    K VijayRaghavan, Satyajit Rath
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    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Inter-species population dynamics enhance microbial horizontal gene transfer and spread of antibiotic resistance

    Robert M Cooper et al.
    Killing their neighbors allows bacteria to steal genes, including antibiotic resistance genes, which we observed under a microscope, quantified, modeled, and predicted potentially guiding strategies to combat it.
    1. Genomics and Evolutionary Biology
    2. Microbiology and Infectious Disease

    Population genomics reveals the origin and asexual evolution of human infective trypanosomes

    William Weir et al.
    The protozoan parasite Trypanosoma brucei gambiense has undergone recent clonal evolution that reveals the theoretically predicted Meselson effect at a genome-wide level.

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