miR-125 functions as a potential dietary restriction mimetic by promoting longevity through regulation of fat metabolism.

Chronic two-photon calcium imaging, optogenetics, and operant behavioral approaches were leveraged to show that hyperactivity, hyperresponsivity, and hypersynchronization in auditory cortex neural ensembles can account for auditory hypersensitivity following acoustic trauma.

Unprecedented 4D spatiotemporal infant regional cerebral blood flow framework and region-specific physiology–function coupling across infancy were elucidated, highlighting strong physiology–function coupling specifically at the default-mode network to meet extraneuronal metabolic demand for network emergence.

Characterization of Tnc as a selective integrin ligand at the Drosophila NMJ allows for unprecedented insights into our understanding of extracellular matrix/integrin interactions at synaptic locations and reveals novel, distinct presynaptic and postsynaptic integrin functions.

Excitatory and inhibitory neurons in the mouse superior colliculus receive comparably strong inputs from retinal ganglion cells, in contrast to the thalamocortical system.

The development of the electrical phenotype of neurons can be precisely quantified and dissected using a combination of multi-variate statistical analyses and a systematic electrophysiological characterization of electrical properties.

A class of interneuron is identified that promotes escape behavior downstream of nociceptor inputs via connections to nociceptive integrator and premotor networks.

Dendrites combine the inputs that they receive from other neurons using calculations that have been optimized for those particular input patterns.

Early deaf human CI users are often insensitive to sub-millisecond interaural time differences (ITDs); however, with synchronized CIs, early deafened rats learned to lateralize small ITDs near 50 µs.

The connection from layer Vb-to-Va neurons, a key component of the canonical hippocampal-cortical output circuit, which is allegedly crucial for memory consolidation, is relatively stronger in lateral entorhinal cortex compared with the medial entorhinal cortex, thus suggesting different operating principles.