N‑terminus of MSL1 protein, involved in dosage compensation in Drosophila, is required for the interaction with non-coding roX2 RNA and the assembly of the complex on the male X chromosome.

Aneuploid human embryonic cells are eliminated by p53-mediated apoptosis in a gene dosage dependent manner.

Robust NMR approach allowed simultaneous detection of substrate cleavage site and real-time kinetics of hydrolysis for Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM, and revealed D-alanyl-glycine activity for LytM.

Across primates, volumes of specific brain regions relate to specific socio-ecological factors, bridging the gap between neuro-cognitive operations from laboratory studies and challenges primates face in their natural environment.

Monosomy in yeast results in numerous gene dosage insufficiencies with potentially lethal collective effect, but strong positive epistasis rooted in the modular structure of cell metabolism cancels it.

Single-cell sequencing and functional analysis identify T cells that can be useful for marker selection and cell therapy in uveal melanoma, a disease largely unresponsive to conventional immune checkpoint therapies.

Limiting cytoplasmic streaming contributes to maintaining spatial separation of the sperm contents from the female meiotic spindle after fertilization.

Natural temperature variation across an optimal reproductive range for wild flies (Drosophila melanogaster) modulates the impact of sexual conflict on female fitness via asymmetric effects on pre- and post-copulatory male harm mechanisms.