237 results found
  1. May 2014

    Episode 12: May 2014

    In this episode we hear about the neuroscience of chewing, skin cancer, African sleeping sickness, an ancient protein complex, and our editor-in-chief shares his thoughts on scientific publishing.
    1. Neuroscience

    Synchronous activity patterns in the dentate gyrus during immobility

    Martin Pofahl et al.
    Two-photon in vivo calcium imaging reveals short time-scale, synchronous and sparse population activity in dentate gyrus that replays place-related information, and is important for formation of dentate-dependent spatial memory.
    1. Neuroscience

    Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons

    Anna J Bowen et al.
    Parabrachial neurons expressing CGRP relay affective components of ascending pain information via distinct thalamic and amygdalar pathways, which together contribute to complementary aspects of adaptive threat responses.
    1. Computational and Systems Biology
    2. Neuroscience

    The head direction circuit of two insect species

    Ioannis Pisokas et al.
    Two evolutionary distant insect species share a common head direction circuit with subtle differences in neuronal morphologies that result in distinct circuit dynamics adapted to each species’ ecology.
    1. Neuroscience

    Synapse-specific opioid modulation of thalamo-cortico-striatal circuits

    William T Birdsong et al.
    By differentially modulating the two major excitatory inputs to the striatum, mu- and delta-opioid receptors regulate the balance between thalamic and cortical inputs to the striatum.
    1. Neuroscience

    Regional complexity in enteric neuron wiring reflects diversity of motility patterns in the mouse large intestine

    Zhiling Li et al.
    Calcium response profiling of large populations of enteric neurons reveals hard-wired neural circuits that reflect the motility program portfolio of the intestinal region they occupy.
    1. Computational and Systems Biology
    2. Neuroscience

    Fast and flexible sequence induction in spiking neural networks via rapid excitability changes

    Rich Pang, Adrienne L Fairhall
    Biologically plausible changes in the excitabilities of single neurons may suffice to selectively modulate sequential network dynamics, without modifying of recurrent connectivity.
    1. Cell Biology
    2. Neuroscience

    Active presynaptic ribosomes in the mammalian brain, and altered transmitter release after protein synthesis inhibition

    Matthew S Scarnati et al.
    Local presynaptic protein synthesis occurring at established nerve terminals in the mammalian brain provides a mechanism for rapidly controlling or restoring presynaptic proteins that affect neurotransmitter release and presynaptic efficiency.
    1. Neuroscience

    Dopamine neuron glutamate cotransmission evokes a delayed excitation in lateral dorsal striatal cholinergic interneurons

    Nao Chuhma et al.
    Dopamine neurons make novel glutamatergic connections to striatal cholinergic interneurons in the lateral dorsal striatum that are mediated by metabotropic glutamate receptors coupled to TrpC channels.
    1. Neuroscience

    Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors

    William Olson et al.
    Single-nociceptor tracing reveals a novel somatotopic organization for the mammalian pain system, and physiological recordings and peripheral optogenetic behavior assays suggest that it is a possible mechanism underlying region-specific pain sensation.

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