129 results found
    1. Cell Biology
    2. Ecology

    Ubiquitous macropinocytosis in anthozoans

    Philippe Ganot et al.
    Macropinocytosis, the process of non-specific endocytosis, is a major gateway for large volumes of surrounding medium and nanoparticles to coral cells.
    1. Cell Biology
    2. Developmental Biology

    Matrix metalloproteinase 1 modulates invasive behavior of tracheal branches during entry into Drosophila flight muscles

    Julia Sauerwald et al.
    Tracheal-derived matrix metalloproteinase 1 activity sustains tracheal branch invasion into myotubes by modulating ECM properties and dynamic behavior of sprouting tip cells.
    1. Computational and Systems Biology
    2. Developmental Biology

    Odd-paired controls frequency doubling in Drosophila segmentation by altering the pair-rule gene regulatory network

    Erik Clark, Michael Akam
    The organisation of the Drosophila embryo into segmental units is orchestrated by combinatorial regulatory interactions between spatially patterned and temporally patterned transcription factors.
    1. Developmental Biology
    2. Neuroscience

    Genetic specification of left–right asymmetry in the diaphragm muscles and their motor innervation

    Camille Charoy et al.
    Analysis of embryonic mouse diaphragm reveals muscle and nerve left–right asymmetries set by a Nodal-dependent genetic cascade, which imprints different molecular signatures to left and right motoneurons that shape their innervation pattern.
    1. Cell Biology
    2. Developmental Biology

    Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling

    Yan Xiong et al.
    Primary cilia on endothelial cells are required for VEGF-A/ VEGFR2-dependent signaling, islet vascularization and, consequently, nutrient delivery and insulin disposal.
    1. Evolutionary Biology

    Resurrection of a global, metagenomically defined gokushovirus

    Paul C Kirchberger, Howard Ochman
    Isolation of a gokushovirus capable of lysogenizing enterobacteria challenges previous notions about the biology of the most prolific phages within the Microviridae and facilitates experimental study in a model organism.
    1. Computational and Systems Biology
    2. Developmental Biology

    Why plants make puzzle cells, and how their shape emerges

    Aleksandra Sapala et al.
    Puzzle-shape cells in the epidermis of many plants form due to a development constraint based on mechanical forces.
    1. Computational and Systems Biology
    2. Developmental Biology

    High-throughput mathematical analysis identifies Turing networks for patterning with equally diffusing signals

    Luciano Marcon et al.
    Realistic reaction-diffusion signaling networks that include cell-autonomous factors can robustly form self-organizing spatial patterns for any combination of diffusion coefficients without requiring differential diffusivity.
    1. Developmental Biology

    Localized JNK signaling regulates organ size during development

    Helen Rankin Willsey et al.
    JNK signaling is active in developing Drosophila tissues and is required for achieving proper organ size.
    1. Microbiology and Infectious Disease

    HetL, HetR and PatS form a reaction-diffusion system to control pattern formation in the cyanobacterium nostoc PCC 7120

    Xiaomei Xu et al.
    Genetic, biochemistry and modeling approaches reveal elements of a Turing-type reaction-diffusion system to control pattern formation in differentiating cyanobacterial filaments.

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