566 results found
    1. Microbiology and Infectious Disease

    Tools and methods for high-throughput single-cell imaging with the mother machine

    Ryan Thiermann, Michael Sandler ... Suckjoon Jun
    A user-friendly pipeline for analysis of time-lapse imaging data from the microfluidic mother machine.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Rapid cell-free forward engineering of novel genetic ring oscillators

    Henrike Niederholtmeyer, Zachary Z Sun ... Sebastian J Maerkl
    Rapid forward engineering can be accomplished using cell-free systems, as demonstrated by the implementation and characterization of novel genetic oscillators in a cell-free system and their consequent transfer to cells.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    History-dependent physiological adaptation to lethal genetic modification under antibiotic exposure

    Yuta Koganezawa, Miki Umetani ... Yuichi Wakamoto
    Single-cell time-lapse imaging and optogenetical gene recombination system uncovered that bacteria cells can overcome a deleterious genetic change of antibiotic resistance gene deletion depending on their environmental histories.
    1. Neuroscience

    Impaired voice processing in reward and salience circuits predicts social communication in children with autism

    Daniel Arthur Abrams, Aarthi Padmanabhan ... Vinod Menon
    Children with autism often 'tune out' the voices in their environment and new results show that impaired processing of voices in the brain's reward system may underlie this social behavior.
    1. Ecology
    2. Evolutionary Biology

    Mandrill mothers associate with infants who look like their own offspring using phenotype matching

    Marie JE Charpentier, Clémence Poirotte ... Julien P Renoult
    Mandrill mothers know best because they use their offspring’s facial resemblance with other infants to guide their social opportunities towards similar-looking ones as an adaptive maternal behavior.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Asymmetric localization of the cell division machinery during Bacillus subtilis sporulation

    Kanika Khanna, Javier Lopez-Garrido ... Elizabeth Villa
    During sporulation, FtsAZ filaments mediating cell division in Bacillus subtilis are positioned asymmetrically around the septum only on the mother cell side, making the septum thinner than during vegetative growth.
    1. Cell Biology
    2. Physics of Living Systems

    Non-genetic inheritance restraint of cell-to-cell variation

    Harsh Vashistha, Maryam Kohram, Hanna Salman
    Quantitative measurement of epigenetic memory and inheritance dynamics.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    'Palaeoshellomics’ reveals the use of freshwater mother-of-pearl in prehistory

    Jorune Sakalauskaite, Søren H Andersen ... Beatrice Demarchi
    Ancient proteomes from tiny shell ornaments were successfully characterised for the first time, showing the unexpected use of mother-of-pearl from local riverine molluscs in both coastal and inland prehistoric sites.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    Protein biogenesis machinery is a driver of replicative aging in yeast

    Georges E Janssens, Anne C Meinema ... Matthias Heinemann
    A comprehensive mapping of the proteome and transcriptome during the complete replicative lifespan of budding yeast predicted an increased abundance of the protein biogenesis machinery is most causal for aging.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Two different cell-cycle processes determine the timing of cell division in Escherichia coli

    Alexandra Colin, Gabriele Micali ... Sven van Teeffelen
    Chromosome replication and a different inter-division process both contribute to division control during unperturbed growth, but if division is delayed by increasing cell width the inter-division process becomes solely rate-limiting.

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