3,826 results found
    1. Neuroscience

    Inferring synaptic inputs from spikes with a conductance-based neural encoding model

    Kenneth W Latimer, Fred Rieke, Jonathan W Pillow
    The conductance-based encoding model creates a new bridge between statistical models and biophysical models of neurons, and infers visually-evoked excitatory and inhibitory synaptic conductances from spike trains in macaque retina.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Highly contiguous assemblies of 101 drosophilid genomes

    Bernard Y Kim, Jeremy R Wang ... Dmitri A Petrov
    One hundred one high-quality drosophilid genomes are released, along with low-cost assembly workflows, as an open community resource for studying genetics, ecology, and evolution in this important model system.
    1. Neuroscience

    Gamma activity accelerates during prefrontal development

    Sebastian H Bitzenhofer, Jastyn A Pöpplau, Ileana Hanganu-Opatz
    Maturation of inhibitory feedback accelerates gamma activity in the medial prefrontal cortex during development.
    1. Neuroscience

    Social aversive generalization learning sharpens the tuning of visuocortical neurons to facial identity cues

    Yannik Stegmann, Lea Ahrens ... Matthias J Wieser
    Measures of visuocortical activity during aversive generalization learning revealed sharpened representations of facial identity, reflecting inhibitory interactions between neuronal populations that represent facial features associated with threat versus safety.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Gut bacterial aggregates as living gels

    Brandon H Schlomann, Raghuveer Parthasarathy
    A theory of gut bacterial aggregation produces a cluster size distribution that matches that of several strains observed in zebrafish, suggesting principles generally applicable to the vertebrate gut.
    1. Cell Biology
    2. Genetics and Genomics

    Rapid re-identification of human samples using portable DNA sequencing

    Sophie Zaaijer, Assaf Gordon ... Yaniv Erlich
    DNA fingerprinting by portable nanopore sequencing is a novel re-identification method with applications in (clinical) laboratories and biobanks.
    1. Structural Biology and Molecular Biophysics

    Mars, a molecule archive suite for reproducible analysis and reporting of single-molecule properties from bioimages

    Nadia M Huisjes, Thomas M Retzer ... Karl E Duderstadt
    Mars provides a software platform for the development of complex single-molecule analysis workflows enabling the discovery and reporting of new biological phenomena with an open data format accessible to everyone.
    1. Computational and Systems Biology
    2. Neuroscience

    Graphical-model framework for automated annotation of cell identities in dense cellular images

    Shivesh Chaudhary, Sol Ah Lee ... Hang Lu
    Unbiased and automatic annotation using structured prediction framework with efficiently built data-driven atlases is more accurate than registration-based methods for cell identifications in dense images and enables fast whole-brain analysis.
    1. Neuroscience

    Multivariate cross-frequency coupling via generalized eigendecomposition

    Michael X Cohen
    A novel methodological framework for cross-frequency coupling and spike-field coherence in multichannel (LFP, EEG, MEG) electrophysiology data reveals new manifestations of coupling dynamics.
    1. Neuroscience

    Altered hippocampal interneuron activity precedes ictal onset

    Mitra L Miri, Martin Vinck ... Jessica A Cardin
    GABAergic interneuron populations in the hippocampus exhibit cell-type-specific patterns of disruption in advance of seizure onset.

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