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    1. Neuroscience

    Body side-specific control of motor activity during turning in a walking animal

    Matthias Gruhn, Philipp Rosenbaum ... Ansgar Büschges
    Turning in an insect is the combined result of body-side-specific modifications in processing of local sensory feedback, and modification of local central pattern generator activity.
    1. Neuroscience

    Analysis of the NK2 homeobox gene ceh-24 reveals sublateral motor neuron control of left-right turning during sleep

    Juliane Schwarz, Henrik Bringmann
    A genetic analysis has identified the cholinergic SIA sublateral motor neurons, which innervate all four body wall muscles separately, as crucial regulators of turning around during sleep in Caenorhabditis elegans.
    1. Neuroscience

    A neural circuit mechanism for regulating vocal variability during song learning in zebra finches

    Jonathan Garst-Orozco, Baktash Babadi, Bence P Ölveczky
    By demonstrating song learning-related synaptic strengthening and pruning in the vocal control circuits of songbirds, and showing how such changes can reduce the sensitivity of the circuit to ‘noisy’ inputs, a simple neural circuit mechanism for regulating motor variability during motor skill learning is identified.
    1. Computational and Systems Biology

    Distributed task-specific processing of somatosensory feedback for voluntary motor control

    Mohsen Omrani, Chantelle D Murnaghan ... Stephen H Scott
    Somatosensory feedback is transmitted to many sensory and motor cortical regions within 25 milliseconds and ongoing behavioural tasks alter the spatiotemporal pattern of this perturbation-related activity, supporting rapid motor responses to attain behavioural goals.
    1. Neuroscience

    Implicit motor adaptation patterns in a redundant motor task manipulating a stick with both hands

    Toshiki Kobayashi, Daichi Nozaki
    A novel motor task reveals the principle of how the motor system coordinates the redundant body for motor adaptation.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch

    Sandeep K Talapatra, Bethany Harker, Julie PI Welburn
    Structural analysis of the kinesin-13 MCAK bound to its C-terminal tail reveals the molecular basis for the conformation of kinesin-13 in solution and the mechanism that triggers long-range conformational changes upon microtubule binding.
    1. Neuroscience

    Motor control of Drosophila feeding behavior

    Olivia Schwarz, Ali Asgar Bohra ... Jan Pielage
    The neuroanatomical and functional analysis of genetically-identified motoneurons controlling all major steps of Drosophila proboscis extension provides new insights into the architecture of a motor circuitry controlling a reaching-like behavior.
    1. Neuroscience

    A size principle for recruitment of Drosophila leg motor neurons

    Anthony W Azevedo, Evyn S Dickinson ... John C Tuthill
    Motor neurons controlling the leg of the fruit fly exhibit a gradient of physiological and functional properties that correlate with the order in which they fire during behavior.
    1. Neuroscience

    Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons

    Zhong L Hua, Philip M Smallwood, Jeremy Nathans
    The signaling molecule Frizzled3 plays a part in the development of the nervous system by controlling the ability of motor neurons to form connections with distant target muscles.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Fundamental constraints in synchronous muscle limit superfast motor control in vertebrates

    Andrew F Mead, Nerea Osinalde ... Coen PH Elemans
    Vertebrate superfast muscles employ similar excitation–contraction strategies but distinct myosin heavy chain genes to allow superfast performance, revealing a maximum speed that cannot be overcome without sacrificing neural control.